“…Psoriasis is heavily influenced by cytokines produced by Th1 cells (IFN-γ, IL-1β, IL-6, and TNF-α) and dendritic cells (IL-10, IL-17, IL-22, and IL-23). All of these cytokines have the potential to be psoriatic indicators. , However, the two primary strategies for addressing psoriasis can be identified as topical drugs (corticosteroids and vitamin D3 derivatives) and systemic drugs (retinoids like acitretin, PDE inhibitors like apremilast, antimetabolites like methotrexate, immunosuppressive drugs like cyclosporine, phototherapies like PUVA, and biologics like etanercept, infliximab, bimekizumab, and guselkumab). − …”