Attention to Food Phosphate and Nutrition Labeling

Watanabe, Marcela Tatiana; Barretti, Pasqual; Júnior, João Garcia Caramori

doi:10.1053/j.jrn.2017.12.013

Cited by 8 publications

(7 citation statements)

References 9 publications

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“… Reduced phosphorus burden: there is less absorbable phosphorus in plant-based proteins given the presence of indigestible phytate binding to plant-based phosphorus. Fruits and vegetables are less likely to have added phosphorus-based preservatives that are often used for meat processing [ 59 , 73 , 74 , 75 ]. Modulation of advanced glycation end products (AGE’s): higher dietary fiber intake results in a favorable modulation of AGE [ 76 ], which can slow CKD progression [ 77 ], enhance GI motility, and lower the likelihood of constipation that is a likely contributor to hyperkalemia.…”

Section: Benefits Of a Plant-dominant Low Protein Dietmentioning

confidence: 99%

Section: Benefits Of a Plant-dominant Low Protein Dietmentioning

confidence: 99%

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Plant-Dominant Low-Protein Diet for Conservative Management of Chronic Kidney Disease

et al. 2020

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Chronic kidney disease (CKD) affects >10% of the adult population. Each year, approximately 120,000 Americans develop end-stage kidney disease and initiate dialysis, which is costly and associated with functional impairments, worse health-related quality of life, and high early-mortality rates, exceeding 20% in the first year. Recent declarations by the World Kidney Day and the U.S. Government Executive Order seek to implement strategies that reduce the burden of kidney failure by slowing CKD progression and controlling uremia without dialysis. Pragmatic dietary interventions may have a role in improving CKD outcomes and preventing or delaying dialysis initiation. Evidence suggests that a patient-centered plant-dominant low-protein diet (PLADO) of 0.6–0.8 g/kg/day composed of >50% plant-based sources, administered by dietitians trained in non-dialysis CKD care, is promising and consistent with the precision nutrition. The scientific premise of the PLADO stems from the observations that high protein diets with high meat intake not only result in higher cardiovascular disease risk but also higher CKD incidence and faster CKD progression due to increased intraglomerular pressure and glomerular hyperfiltration. Meat intake increases production of nitrogenous end-products, worsens uremia, and may increase the risk of constipation with resulting hyperkalemia from the typical low fiber intake. A plant-dominant, fiber-rich, low-protein diet may lead to favorable alterations in the gut microbiome, which can modulate uremic toxin generation and slow CKD progression, along with reducing cardiovascular risk. PLADO is a heart-healthy, safe, flexible, and feasible diet that could be the centerpiece of a conservative and preservative CKD-management strategy that challenges the prevailing dialysis-centered paradigm.

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Section: Benefits Of a Plant-dominant Low Protein Dietmentioning

confidence: 99%

Section: Benefits Of a Plant-dominant Low Protein Dietmentioning

confidence: 99%

Plant-Dominant Low-Protein Diet for Conservative Management of Chronic Kidney Disease

et al. 2020

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“…11 (3) There is less absorbable phosphorus in plant-based protein given the preponderance of indigestible phytate as the main source of phosphorus and given that fresh fruits or vegetables are less likely to have added phosphorus-based preservatives that are often used for meat processing. 12,13 (4) Higher dietary fiber intake, in addition to a favorable modulation of advanced glycation end products, 14 enhances gastrointestinal motility and lowers the likelihood of constipation, which is a likely contributor to hyperkalemia. (5) A vegan diet based on fresh fruits and vegetables lessen the likelihood of exposure to potassium-based additives.…”

mentioning

confidence: 99%

Does Kidney Longevity Mean Healthy Vegan Food and Less Meat or Is Any Low-Protein Diet Good Enough?

Kalantar-Zadeh

Moore

2019

Journal of Renal Nutrition

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“…Phosphate ions are absorbed in the small intestine by a Na + -dependent cotransporter and by passive diffusion [93,94]. High phosphate intake, derived from the consumption of foods rich in additives [95,96] or from initial chronic kidney disease (CDK) [97,98] is a real threat that often passes undiscovered and results in hyperphosphatemia. Increased phosphate concentrations can affect iron metabolism both before its absorption and in the bloodstream; this anion can efficiently chelate iron ions as proved in a recent experiment where it deprived bacteria of iron ions [99].…”

Section: Nutritional Sources That Hinder Iron Absorptionmentioning

confidence: 99%

Iron-Enriched Nutritional Supplements for the 2030 Pharmacy Shelves

et al. 2021

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Iron deficiency (ID) affects people of all ages in many countries. Due to intestinal blood loss and reduced iron absorption, ID is a threat to IBD patients, women, and children the most. Current therapies can efficiently recover normal serum transferrin saturation and hemoglobin concentration but may cause several side effects, including intestinal inflammation. ID patients may benefit from innovative nutritional supplements that may satisfy iron needs without side effects. There is a growing interest in new iron-rich superfoods, like algae and mushrooms, which combine antioxidant and anti-inflammatory properties with iron richness.

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Attention to Food Phosphate and Nutrition Labeling

Cited by 8 publications

References 9 publications

Plant-Dominant Low-Protein Diet for Conservative Management of Chronic Kidney Disease

Plant-Dominant Low-Protein Diet for Conservative Management of Chronic Kidney Disease

Does Kidney Longevity Mean Healthy Vegan Food and Less Meat or Is Any Low-Protein Diet Good Enough?

Iron-Enriched Nutritional Supplements for the 2030 Pharmacy Shelves

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