Attention‐deficit hyperactivity symptoms and risk of alcohol use relapse

Kawata, Takahiro; Sugihara, Genichi; Kakibuchi, Yoichi; Tomitaka, Midori; Miyajima, Miho; Matsushima, Eisuke; Takeuchi, Takashi; Takahashi, Hidehiko

doi:10.1002/npr2.12312

Cited by 4 publications

(1 citation statement)

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“… 44 And also similar result was found in the relationship of increased ASUD relapse in 45 studies of people with alcohol use disorders (total n = 25 076), psychiatric comorbidity, usually diagnosed as mood disorder or attention deficit hyperactivity disorder (ADHD), was significantly associated with an increased risk of relapse. 13 , 45 …”

Section: Clinical and Research Consequencesmentioning

confidence: 99%

Factors Associated with Relapses in Alcohol and Substance Use Disorder

Yazıcı,

Bardakçı

2024

The Eurasian Journal of Medicine

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Alcohol and substance use disorder (ASUD) is a chronic condition featuring relapses and remissions. Due to their multifactorial nature, the causes of relapses in ASUD are not fully understood and it is important to update the information. Therefore, we aimed to provide an update on research examining factors associated with relapses, organized into sections. Factors such as early age of onset, dysfunction in the brain reward system, poor physical health, sleep disturbance, comorbid psychiatric disorders, severity of ASUD, craving, low self-efficacy, negative life events, and low socioeconomic status have been consistently shown to increase the relapse rate of ASUD. Conversely, factors such as positive family functioning, strong social support, treatment motivation and regular medication appear to decrease relapse rates. Studies on gender and genetic factors have yielded mixed results and no consistent relationship with relapses has been found. While pharmaceutical agents such as methadone, buprenorphine and naltrexone are effective in preventing relapse in opioid and alcohol use disorders; there are no agents proven to be effective in other substance use disorders. Psychotherapeutic approaches, including motivational interviewing, cognitive behavioral therapy, 12-step programs and contingency management have been demonstrated to be effective. The treatment of addiction to substances is intricate and necessitates biopsychosocial interventions. However, despite all treatments, high relapse rates indicate the necessity for social support and rehabilitation services. In the light of the data obtained, the factors affecting relapses in patients with ASUD can be determined and appropriate interventions and therapeutic approaches can be used to prevent relapses.

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Section: Clinical and Research Consequencesmentioning

confidence: 99%

Factors Associated with Relapses in Alcohol and Substance Use Disorder

Yazıcı,

Bardakçı

2024

The Eurasian Journal of Medicine

View full text Add to dashboard Cite

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Attention‐deficit hyperactivity symptoms and risk of alcohol use relapse

Kawata

Sugihara

Kakibuchi³

et al. 2022

Neuropsychopharm Rep

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Aim Alcohol use disorder (AUD) is frequently accompanied by comorbid attention‐deficit hyperactivity disorder (ADHD). Comorbid ADHD has been reported to increase the severity of AUD. We investigated whether ADHD severity also influences AUD relapse risk at baseline and after inpatient treatment. Methods In this study, 187 AUD patients admitted to Narimasu Kosei Hospital from October 2019 to March 2021 were included in the analysis. According to the Adult ADHD Self‐Report Scale (ASRS), participants were divided into two groups: ASRS+ with ADHD characteristics (n = 43) and ASRS− with low/no ADHD characteristics (n = 144). Groups were compared for AUD relapse risk at the start of treatment (baseline) and before hospital discharge using the multidimensional Alcohol Relapse Risk Scale (ARRS). The change in relapse risk during hospitalization was also compared by assessment of the interaction between groups (ASRS+ vs. ASRS−) and time (at discharge vs. baseline). Results The total ARRS score and dimension subscores for stimulus‐induced vulnerability and emotionality problems were significantly higher in the ASRS+ group at baseline and before discharge compared to the ASRS− group. There was a significant group × time interaction indicating less improvement of stimulus‐induced vulnerability during inpatient treatment among the ASRS+ group compared to the ASRS− group. Conclusions Our findings suggest that AUD patients with ADHD characteristics have a higher risk of relapse both at baseline and after inpatient treatment. Stimulus‐induced vulnerability to relapse is less likely to improve with treatment in patients with ADHD characteristics.

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