Attack elicited by forebrain and hypothalamic stimulation in the chicken

Putkonen, P. T. S.

doi:10.1007/bf01901167

Cited by 31 publications

(18 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This region in birds is also functionally similar to the mammalian meAMY. When the nucleus taeniae is electrically stimulated in chicken, the animals become more aggressive (Putkonen, 1966). In a choice paradigm, female zebra finch (Taeniopygia guttata) never choose males with lesions to the nucleus taeniae, as they display less sexually motivated behavior (Ikebuchi et al, 2009).…”

Section: Birdsmentioning

confidence: 99%

The Vertebrate mesolimbic reward system and social behavior network: A comparative synthesis

O’Connell

Hofmann

2011

J of Comparative Neurology

856

879

View full text Add to dashboard Cite

All animals evaluate the salience of external stimuli and integrate them with internal physiological information into adaptive behavior. Natural and sexual selection impinge on these processes, yet our understanding of behavioral decision-making mechanisms and their evolution is still very limited. Insights from mammals indicate that two neural circuits are of crucial importance in this context: the social behavior network and the mesolimbic reward system. Here we review evidence from neurochemical, tract-tracing, developmental, and functional lesion/stimulation studies that delineates homology relationships for most of the nodes of these two circuits across the five major vertebrate lineages: mammals, birds, reptiles, amphibians, and teleost fish. We provide for the first time a comprehensive comparative analysis of the two neural circuits and conclude that they were already present in early vertebrates. We also propose that these circuits form a larger social decision-making (SDM) network that regulates adaptive behavior. Our synthesis thus provides an important foundation for understanding the evolution of the neural mechanisms underlying reward processing and behavioral regulation. J. Comp. Neurol. 519:3599-3639, 2011. INDEXING TERMS: social behavior; comparative neuroanatomy; amphibian; reptile; bird; teleost; reward system; social behavior network; limbic system; neural circuitsThroughout their lives, all animals constantly face situations that provide either challenges (e.g., aggression, predation) or opportunities (e.g., reproduction, foraging, habitat selection) (for a detailed review, see O'Connell and Hofmann, 2011). In all cases, environmental cues are processed by sensory systems into a meaningful biological signal while internal physiological cues (e.g., condition, maturity) and prior experience are integrated at the same time. This process usually results in behavioral actions that are adaptive, i.e., beneficial to the animal. To accomplish this, an animal's nervous system must evaluate the salience of a stimulus and elicit a context-appropriate behavioral response. Despite tremendous progress in understanding the ecology and evolution of social behavior (Lorenz, 1952;Tinbergen, 1963;Lehrman, 1965;von Frisch, 1967;Krebs and Davies, 1993;Stephens, 2008), it is less understood where in the brain these decisions (e.g., about mate choice or territory defense) are made and how these brain circuits have arisen over the course of vertebrate evolution.Recent research has begun to decipher the neural basis of social decision-making. In mammals in particular, the neural circuits that evaluate stimulus salience and/or regulate social behavior have been uncovered to some degree: the mesolimbic reward system and social behavior network (Fig. 1). It is becoming increasingly clear that the reward system (including but not limited to the midbrain dopaminergic system) is the neural circuit where the salience of an external stimulus is evaluated (Deco and Rolls, 2005;Wickens et al., 2007), as appetitive beh...

show abstract

Section: Birdsmentioning

confidence: 99%

The Vertebrate mesolimbic reward system and social behavior network: A comparative synthesis

O’Connell

Hofmann

2011

J of Comparative Neurology

856

879

View full text Add to dashboard Cite

show abstract

“…We recently performed chronic in vivo recordings of VMHvl activity in male mice, demonstrating differential responses to males and females: although agonistic interactions with males induce increased VMHvl activity in male mice, sexual interactions with females cause suppression of VMHvl activity (Lin et al, 2011). Here we further analyze these and other data to quantify the relationship between VMHvl activity and sensory and movement parameters during male interaction.…”

Section: Introductionmentioning

confidence: 95%

“…Methods for physiological recording in freely moving animals were described previously (Lin et al, 2011). Briefly, a movable bundle of 16 tungsten microwires (13 m in diameter each; California Fine Wire) was implanted into the VMHvl during stereotactic surgery.…”

Section: Electrophysiological Recording and Behavior Annotationmentioning

confidence: 99%

“…In particular, Kruk et al (1983) mapped out a distributed "hypothalamic attack area" in rats by comparing the effects of hundreds of electrode stimulation sites. Our recent studies in mice demonstrated that optogenetic stimulation of the ventromedial hypothalamus, ventrolateral area (VMHvl), but not its surrounding regions, promotes attack toward males as well as castrated male and female conspecific intruders, whereas pharmacogenetic inactivation of the region suppresses naturally occurring aggression (Lin et al, 2011). Despite the confluence of these results, the precise role of the hypothalamus in promoting aggression remains debatable.…”

Section: Introductionmentioning

confidence: 99%

“…For example, hypothalamic stimulation-induced attack usually appears quickly and dissipates within seconds after stimulation is terminated, and certain aggressive movements observed during natural aggression are absent from stimulation-evoked attack in rats (Siegel et al, 1999). Stimulation can also sometimes drive attack toward nonthreatening targets that are not normally the targets of aggression (Siegel et al, 1999;Lin et al, 2011). However, hypothalamic stimulation activates the hypothalamic-pituitary adrenal axis and increases stress hormone release even in the absence of a social target or any overt motor responses (Kruk et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Decoding Ventromedial Hypothalamic Neural Activity during Male Mouse Aggression

et al. 2014

View full text Add to dashboard Cite

The ventromedial hypothalamus, ventrolateral area (VMHvl) was identified recently as a critical locus for inter-male aggression. Optogenetic stimulation of VMHvl in male mice evokes attack toward conspecifics and inactivation of the region inhibits natural aggression, yet very little is known about its underlying neural activity. To understand its role in promoting aggression, we recorded and analyzed neural activity in the VMHvl in response to a wide range of social and nonsocial stimuli. Although response profiles of VMHvl neurons are complex and heterogeneous, we identified a subpopulation of neurons that respond maximally during investigation and attack of male conspecific mice and during investigation of a source of male mouse urine. These "male responsive" neurons in the VMHvl are tuned to both the inter-male distance and the animal's velocity during attack. Additionally, VMHvl activity predicts several parameters of future aggressive action, including the latency and duration of the next attack. Linear regression analysis further demonstrates that aggressionspecific parameters, such as distance, movement velocity, and attack latency, can model ongoing VMHvl activity fluctuation during inter-male encounters. These results represent the first effort to understand the hypothalamic neural activity during social behaviors using quantitative tools and suggest an important role for the VMHvl in encoding movement, sensory, and motivation-related signals.

show abstract

Aggressive behavior of pigeons: Suppression by archistriatal lesions

Ramírez

Delius

1979

Aggr. Behav.

View full text Add to dashboard Cite

Attack elicited by forebrain and hypothalamic stimulation in the chicken

Cited by 31 publications

References 0 publications

The Vertebrate mesolimbic reward system and social behavior network: A comparative synthesis

The Vertebrate mesolimbic reward system and social behavior network: A comparative synthesis

Decoding Ventromedial Hypothalamic Neural Activity during Male Mouse Aggression

Aggressive behavior of pigeons: Suppression by archistriatal lesions

Contact Info

Product

Resources

About