Atrial fibrillation ablation: contemporary practice and future potential

Kojodjojo, Pipin; Davies, D. Wyn

doi:10.1136/hrt.2010.206888

Cited by 3 publications

(2 citation statements)

References 22 publications

(15 reference statements)

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“…The use of cardiac rhythm control medication with catheter ablation is one of the effective ways to treat AF, especially in the early phase 7 – 10 . In addition to the experience of the physician, the treatment outcome of AF by catheter ablation is closely correlated with the LA electrical-signal distribution and LA architecture 11 – 13 . Therefore, diagnostic tools, including cardiac catheterisation, electrocardiography (ECG), electrophysiological study (EPS), magnetic resonance imaging (MRI) and cardiac computed tomography (CT), are needed during the treatment process.…”

Section: Introductionmentioning

confidence: 99%

Left Atrium Wall-mapping Application for Wall Thickness Visualisation

Sun

Yun

Mok

et al. 2018

Sci Rep

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The measurement method for the LA wall thickness (WT) using cardiac computed tomography (CT) is observer dependent and cannot provide a rapid and comprehensive visualisation of the global LA WT. We aim to develop a LA wall-mapping application to display the global LA WT on a coplanar plane. The accuracy, intra-observer, and inter-observer reproducibility of the application were validated using digital/physical phantoms, and CT images of eight patients. This application on CT-based LA WT measures were further validated by testing six pig cardiac specimens. To evaluate its accuracy, the expanded maps of the physical phantom and pig LA were generated from the CT images and compared with the expanded map of the digital phantom and LA wall of pig heart. No significant differences (p > 0.05) were found between physical phantom and digital phantom as well as pig heart specimen and CT images using our application. Moreover, the analysis was based on the LA physical phantom or images of clinical patients; the results consistently demonstrated high intra-observer reproducibility (ICC > 0.9) and inter-observer reproducibility (ICC > 0.8) and showed good correlation between measures of pig heart specimen and CT data (r = 0.96, p < 0.001). The application can process and analyse the LA architecture for further visualisation and quantification.

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Section: Introductionmentioning

confidence: 99%

Left Atrium Wall-mapping Application for Wall Thickness Visualisation

Sun

Yun

Mok

et al. 2018

Sci Rep

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“…Alternatively, minimally-invasive catheter ablation can be used to create lesions by burning or freezing the atrial tissue. Current catheter ablation procedures are tedious, time-consuming, and result in significant X-ray exposure to the patient and medical team [5], [6]. Success requires highly skilled catheter manipulation in the beating heart, and constant surface contact for transmural and continuous lesions [7], [8].…”

Section: Introductionmentioning

confidence: 99%

Path optimization and control of a shape memory alloy actuated catheter for endocardial radiofrequency ablation

Wiest

Buckner

2015

Robotics and Autonomous Systems

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This paper introduces a real-time path optimization and control strategy for shape memory alloy (SMA) actuated cardiac ablation catheters, potentially enabling the creation of more precise lesions with reduced procedure times and improved patient outcomes. Catheter tip locations and orientations are optimized using parallel genetic algorithms to produce continuous ablation paths with near normal tissue contact through physician-specified points. A nonlinear multivariable control strategy is presented to compensate for SMA hysteresis, bandwidth limitations, and coupling between system inputs. Simulated and experimental results demonstrate efficient generation of ablation paths and optimal reference trajectories. Closed-loop control of the SMA-actuated catheter along optimized ablation paths is validated experimentally.

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