Atrial Ejection Force in Systemic Autoimmune Diseases

Naito, Junko; Tony, Hans‐Peter; Inselmann, G.

doi:10.1159/000006985

Cited by 10 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The method used for assessing LASF was initially described by Manning in 1993 [5] and was subsequently applied by several investigators [1,3,6]. It assumes a constant circular area for the estimation of the mitral orifice and measures peak atrial velocity of transmitral flow.…”

Section: Introductionmentioning

confidence: 99%

Left atrial systolic force: comparison between two methods for the noninvasive assessment of left atrial systolic function

Cioffi¹,

Chinali²,

Mureddu³

et al. 2008

Journal of Cardiovascular Medicine

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Left atrial systolic force: comparison between two methods for the noninvasive assessment of left atrial systolic function

Cioffi¹,

Chinali²,

Mureddu³

et al. 2008

Journal of Cardiovascular Medicine

View full text Add to dashboard Cite

show abstract

“…Parameters derived are: E = Peak early diastolic left ventricular inflow velocity; A = left ventricular inflow velocity at atrial contraction; DT = deceleration (by extrapolation of E to the baseline); IVRT = isovolumetric relaxation time; AVCA = aortic valve closure artifact((31)). …”

Section: Methodsmentioning

confidence: 99%

Left atrial function for outcome prediction in severe sepsis and septic shock: An echocardiographic study

Omar¹,

Rahman²,

Abuhasna³

2009

Indian Journal of Critical Care Medicine

View full text Add to dashboard Cite

Left ventricular function and B-type natriuretic peptide (BNP) assessments are used to predict mortality in septic patients. Left atrial function has never been used to prognosticate outcome in septic patients.Objectives:To assess if deterioration of left atrial function in patients with severe sepsis and septic shock could predict mortality.Methods:We studied 30 patients with severe sepsis or septic shock with a mean age of 49.8±16.17. Echocardiographic parameters were measured on admission, Day 4, and Day 7, which comprised left ventricular ejection fraction (EF), and atrial function that is expressed as atrial ejection force (AEF). All patients were subjected to BNP assay as well. Multivariate analyses adjusted for APACHE II score was used for mortality prediction.Results:The underlying source for sepsis was lung in 10 patients (33%), blood in 7 patients (23.3%), abdomen in 7 patients (23.7%), and 3 patients (10%) had UTI as a cause of sepsis. Only one patient had CNS infection. In-hospital mortality was 23.3% (7 patients). Admission EF showed a significant difference between survivors and non survivors, 49.01±6.51 vs.. 56.44±6.93% (P<0.01). On the other hand, admission AEF showed insignificant changes between the same groups, 10.9±2.81 vs. 9.41±2.4 k/dynes P=0.21, while BNP was significantly higher in the non survivors, 1123±236.08 vs. 592.7±347.1 pg/ml (P<0.001). The predicatable variables for mortality was Acute Physiology and Chronic Health Evaluation II score, BNP, then EF.Conclusion:In septic patients, left atrial function unlike the ventricular function and BNP levels can not be used as an independent predictor of mortality.

show abstract

Augmentation of Left Atrial Contractile Function: A Herald of Iron Overload in Patients with Beta Thalassemia Major

et al. 2010

View full text Add to dashboard Cite

Early detection of myocardial iron overload is crucial for optimal management of patients with beta thalassemia major, which could lead to intensification of iron chelating therapy. In this study, we evaluate the conventional echocardiography and tissue Doppler imaging measurements in patients with beta thalassemia major and further introduce the assessment of atrial ejection force as a feasible price-saving approach for early detection of myocardial iron overload. During a 1-year period, 42 cases of beta thalassemia major aged <21 years and with preserved systolic function were evaluated with magnetic resonance T2* imaging (MRI T2*), conventional echocardiography, and tissue Doppler imaging techniques. Patients were classified into two groups according to their myocardial MRI T2* values, with and without critical iron loading. All patients with echocardiographic evidence of moderate and severe stages of diastolic dysfunction showed critical iron loading in their MRI T2*. After excluding those patients with severe and moderate ventricular diastolic filling abnormality, the atrial ejection force index (P = 0.002) and a number of volume indexes of the left atrium showed a significant difference between the two groups. None of the tissue Doppler imaging measurements showed a statistically significant difference between the two groups. The atrial ejection force index of 7.41, with a sensitivity of 93% and a specificity of 74%, was suggested to detect critical cardiac iron loading. These results imply that combining the atrial ejection force index with the transmitral-derived echocardiographic assessment is a feasible way to detect early stages of myocardial iron overload in patients with beta thalassemia major.

show abstract

Atrial Ejection Force in Systemic Autoimmune Diseases

Cited by 10 publications

References 17 publications

Left atrial systolic force: comparison between two methods for the noninvasive assessment of left atrial systolic function

Left atrial systolic force: comparison between two methods for the noninvasive assessment of left atrial systolic function

Left atrial function for outcome prediction in severe sepsis and septic shock: An echocardiographic study

Augmentation of Left Atrial Contractile Function: A Herald of Iron Overload in Patients with Beta Thalassemia Major

Contact Info

Product

Resources

About