“…We report an unusual case of a collegiate baseball pitcher with pain and wrist extension weakness after short periods of pitching, consistent with an exertional compressive neuropathy of the radial nerve where it pierces the lateral intermuscular septum. Compressive neuropathy of the radial nerve can result as a consequence of trauma, such as a diaphyseal humerus fracture [10][11][12] , but can also occur without trauma, as a result of repetitive elbow extension and triceps contraction, in particular the lateral head, leading to pain and weakness 13,14 . In this case, symptoms of pain and weakness occurred only transiently with overhead pitching activities.…”