Atom transfer radical-polymerized cationic shells on gold nanoparticles for near infrared-triggered photodynamic therapy of tumor-bearing animals

Abstract

Gold nanoparticles (AuNPs) were surface-engineered with a cationic corona to enhance the incorporation of photosensitizers for PDT.

Light‐Triggered Structural Modulation of Nanofibrous Meshes to Promote Deep Penetration of Cultured Cells

“…[ 49,50 ] In our previous study, the production of singlet oxygen was reported to be almost 100% after 10 min of irradiation using the same laser. [ 29 ] Additionally, there were no significant differences between 24 and 48 h incubation time ( p < 0.05). Thus, we speculated that incubating cells with light pretreated NFs would be less harmful to cells than irradiating them during the coculture of cells and NFs.…”

“…[ 26 ] Ce6 has been known to be a popular photosensitizer, and the generation of ROS was induced by 660 nm laser irradiation. [ 27–29 ]…”

Photodynamic Alginate Zn-MOF Thermosensitive Hydrogel for Accelerated Healing of Infected Wounds

“…The characteristic absorption peaks of Ce6 at 400 and 660 nm were red-shifted to 410 and 667 nm in Ce6@MOF, respectively (Figure 1a). In the Raman spectra of Ce6, MOF, and Ce6@MOF (Figure 1b), Ce6@MOF showed the characteristic bonds of Ce6 at 800 cm −1 (porphyrins at the pyrrole rings of Ce6), 1426 cm −1 (C−N stretching), and 1690 cm −1 (C−C), 32 indicating the successful encapsulation of Ce6 into MOF. The encapsulation efficiency in Ce6@MOF was S1, the encapsulation efficiency of Ce6 at the concentration of 0.5 mg/ mL did not change significantly compared with that of 0.2 mg/ mL.…”

Tumor-targeting biomimetic sonosensitizer-conjugated iron oxide nanocatalysts for combinational chemodynamic–sonodynamic therapy of colorectal cancer

“…[5][6][7][8] Although traditional radiotherapy, chemotherapy and their combined therapy have made great progress in cancer treatment, the strong side effects and high toxicity in vivo are still invincible challenges that cannot be overlooked. [9][10][11] To detour these problems, the rapid progress of nanomaterials and nanomedicines provides possible strategies for cancer treatment, such as sonodynamic therapy (SDT). [12][13][14] In principle, the SDT method is to adopt ultrasound (US)-derived mechanical force to induce the massive production of harmful reactive oxygen species (ROS) for destroying cancer cells.…”