Atom-efficient and environment-friendly multicomponent synthesis of amidoalkyl naphthols catalyzed by P2O5

Efficient and solvent-free synthesis of 1-amidoalkyl-2-naphthols using N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide

“…Therefore, the following mechanism can be suggested for the synthesis of amidoalkyl naphthols (Scheme 2) [16][17][18][19].…”

“…In recent years, ZrOCl 2 [9] [14], VB 1 [15], P 2 O 5 [16], Yb(OTf) 3 Bmim BF 4 [17], CuPMo [18], NKC-9 [19], and H 3 Mo 12 O 40 P [20] have been utilized, as catalysts, for this synthesis. In continuation of our interest in the application of N,N,N',N'-tetrabromobenzene-1,3-disulfonamide [TBBDA] [21] (Fig.…”

ZrOCl2·8H2O as an Efficient Catalyst for the Pseudo Four-Component Synthesis of Benzopyranopyrimidines

“…Solventfree multicomponent reactions offer a wide range of possibilities for the efficient construction of highly complex molecules in a single step, thus avoiding complicated purification operations and allowing savings of both solvents and reagents. 5,6 Functionalized nitrogen-heterocycles play a prominent role in medicinal chemistry and they have been intensively used as scaffolds for drug development. In this context fused pyrimidine derivatives are of particular interest because of their pharmacological profile.…”

One-pot Multi-component Synthesis of Amidoalkyl Naphthols with Potassium Hydrogen Sulfate as Catalyst under Solvent-free Condition

“…al 2008), Brösted acidic ionic liquid (Hajipour, A. R. et. al 2009), P 2 O 5 (Nandi, G. C. et. al 2009), cyanuric chloride (Mahdavinia, G. H. et.…”