Atmospheric Pressure Plasma Surface Treatment of Polymers and Influence on Cell Cultivation

Abstract

Atmospheric plasma treatment is an effective and economical surface treatment technique. The main advantage of this technique is that the bulk properties of the material remain unchanged while the surface properties and biocompatibility are enhanced. Polymers are used in many biomedical applications; such as implants, because of their variable bulk properties. On the other hand, their surface properties are inadequate which demands certain surface treatments including atmospheric pressure plasma treatment. In biomedical applications, surface treatment is important to promote good cell adhesion, proliferation, and growth. This article aim is to give an overview of different atmospheric pressure plasma treatments of polymer surface, and their influence on cell-material interaction with different cell lines.

Core/Shell Glycine-Polyvinyl Alcohol/Polycaprolactone Nanofibrous Membrane Intended for Guided Bone Regeneration: Development and Characterization

“…Generally, cells adhere to moderately hydrophilic surfaces; therefore, in scaffold fabrication, many surface modification techniques are applied to hydrophobic surfaces, such as plasma treatment [43]. The PCL fabricated membrane showed a hydrophobic surface with an average C.A of almost 100 • .…”

A vascularized crypt-patterned colon model for high-throughput drug screening and disease modelling

“…Air plasma treatment through temporary hydroxyl deposition made the surface more hydrophilic but was insufficient in preventing adhesion. 34,35 Both polyethylene glycol (PEG) photografting and anti-adherence rinsing solution coating produced intact crypt-patterned gels. Since PEG photografting involved more complex and time-consuming steps, we finalized on using simple antiadherence coating solution.…”

Surface modifications of biomaterials in different applied fields

“…90 This method has the advantage of only changing the surface properties of the material, such as surface chemistry, roughness, surface charge, and also enhancing the biocompatibility of the material, while the bulk properties of the material remain unchanged. 90,91 Gas plasmas can be generated under both atmospheric pressure and low-pressure conditions. 92 A large number of gases can be used in plasma, including argon, nitrogen, and argon–oxygen mixture, which are used to generate functional groups or free radicals on the surface of materials.…”