Atmospheric-pressure plasma sources for biomedical applications

Park, G Y; Park, S J; Choi, Moon‐Hee; Koo, Il Gyo; Byun, June Ho; Hong, Jin Woo; Sim, Jae‐Yoon; Collins, G. J.; Lee, J K

doi:10.1088/0963-0252/21/4/043001

Cited by 327 publications

(204 citation statements)

References 167 publications

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“…For application-adapted plasma devices, several physical and technical concepts are existing for flat DBD-based plasma devices and plasma jet arrangements for large-area treatment, catheter-like plasma devices for endoscopic application as well as plasma devices to reach difficult to access areas in cavities e.g. for dental applications [2,16,17].…”

Section: Medical Application Of Capmentioning

confidence: 99%

Low temperature plasma applications in medicine

2016

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Section: Medical Application Of Capmentioning

confidence: 99%

Low temperature plasma applications in medicine

2016

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“…Atmospheric pressure plasma jet is one of the most efficient sources for decontamination [45][46][47][48].…”

Section: Bacteria Decontaminationmentioning

confidence: 99%

Single channel atmospheric pressure transporting plasma and plasma stream demultiplexing: physical characterization and application toE. colibacteria inactivation

Omran¹,

Sohbatzadeh²,

Siadati³

et al. 2017

J. Phys. D: Appl. Phys.

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In this article, we developed transporting plasma sources that operate at atmospheric pressure. The effect of electrode configuration on plasma transporting was investigated. In order to increase the transporting plasma cross section, we converted a plasma stream into four plasma channels by a cylindrical housing. Electron-excitation and rotational temperatures were estimated using optical emission spectroscopy. Furthermore, the electrical and temporal characteristics of the plasma, discharge power and charge deposition on the target were investigated. The propagation characteristics of single and multi-channel transporting plasma were compared with the same crosssection area. Two configurations for multi-channels were designed for this purpose. Escherichia coli bacteria were exposed to the single and multi-channel transporting discharge for different time durations. After exposure, the results indicated that the inactivation zones were significantly increased by a multi-channel transporting plasma.Finally, E. coli inactivation by those plasma apparatuses was compared with that of several standard antimicrobial test discs such as Gentamicin, Tetracycline, Amoxicillin and Cefixime.

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“…The progress in plasma medicine research has been fast and fruitful in recent years [1][2][3][4]. One of its most appealing medical applications is treatment of living cells and tissues with cold plasmas (e.g., [5][6][7][8][9][10][11][12][13][14][15]).…”

Section: Introductionmentioning

confidence: 99%

Safeguarding against Inactivation Temperatures during Plasma Treatment of Skin: Multiphysics Model and Phase Field Method

Beni

2017

MCA

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Abstract:One of the most appealing applications of cold plasmas is medical treatment of the skin. An important concern is the capability to safeguard the non-targeted cells against inactivation temperatures during the plasma treatment. Unfortunately, it is problematic to experimentally determine the highest transient temperatures in these cells during the plasma treatment. In the present work, a complete multiphysics model was built based on finite element analysis using phase field method coupled with heat transfer and fluid dynamics to study the discharge phenomenon of cold plasma with helium carrier gas ejected out of a tube for skin treatment. In such plasmas with carrier gas, the fractions of plasma constituents are small compared to the carrier gas, so thermofluid analysis is needed for the carrier gas as the major contributor to the fluid and heat flow. The phase field method has been used to capture the moving helium gas in air, which has enabled us to compute fluid dynamics parameters for each phase individually. In addition to computational fluid dynamic analyses, we have also considered heat transfer in the fluids and to the skin using the Fourier law of heat conduction, which led to a multiphysics system. In the present paper, various flow velocities and tube-to-target distances (TTDs) have been considered to reveal the dependence of the fluid discharge output parameters on the flow and efficiency of heat transfer to the skin and the surrounding environment. The built model is a useful tool for future development of plasma treatment devices and to safeguard the non-targeted cells against inactivation temperatures.

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Atmospheric-pressure plasma sources for biomedical applications

Cited by 327 publications

References 167 publications

Low temperature plasma applications in medicine

Low temperature plasma applications in medicine

Single channel atmospheric pressure transporting plasma and plasma stream demultiplexing: physical characterization and application toE. colibacteria inactivation

Safeguarding against Inactivation Temperatures during Plasma Treatment of Skin: Multiphysics Model and Phase Field Method

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