2017
DOI: 10.3390/mca22010024
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Safeguarding against Inactivation Temperatures during Plasma Treatment of Skin: Multiphysics Model and Phase Field Method

Abstract: Abstract:One of the most appealing applications of cold plasmas is medical treatment of the skin. An important concern is the capability to safeguard the non-targeted cells against inactivation temperatures during the plasma treatment. Unfortunately, it is problematic to experimentally determine the highest transient temperatures in these cells during the plasma treatment. In the present work, a complete multiphysics model was built based on finite element analysis using phase field method coupled with heat tr… Show more

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Cited by 3 publications
(2 citation statements)
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References 30 publications
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“…For example, in a previous study, the plasma frequency was set to be at 5 kHz and the pulse width was set at 0.50 µs [22]. Moreover, the fractions of plasma constituents were found to be small and therefore no significant additional heat was produced as a result of reactions in the discharge, so the bulk temperature of the carrier gas would be the dominating factor in determining the plume temperature [27][28][29].…”
Section: Introductionmentioning
confidence: 99%
“…For example, in a previous study, the plasma frequency was set to be at 5 kHz and the pulse width was set at 0.50 µs [22]. Moreover, the fractions of plasma constituents were found to be small and therefore no significant additional heat was produced as a result of reactions in the discharge, so the bulk temperature of the carrier gas would be the dominating factor in determining the plume temperature [27][28][29].…”
Section: Introductionmentioning
confidence: 99%
“…Such theoretical models, particularly in a time-dependent (i.e., dynamic) manner, would be critical in the success in applying CAPs to dentistry. Our group previously examined the interaction of CAPs with water medium [44], blood [45], and skin [46] using the finite element method (FEM). More recently, we studied the transport mechanism of OH radicals in CAP discharges and their dispersion and distribution over a skin layer [47], which considered both the diffusion and convection mechanisms in a two-phase flow system (i.e., CAP carrier gas and ambient air).…”
Section: Introductionmentioning
confidence: 99%