Atmospheric pressure cold plasma leads to apoptosis in saccharomyces cerevisiae by accumulation of intracellular reactive oxygen species and calcium

Ma, Ruonan; Tian, Ying; Zhang, Qian; Fang, Jing; Zhang, Jue; Feng, Hongqing; Liang, Yi

doi:10.1109/plasma.2013.6634816

Cited by 17 publications

(26 citation statements)

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“…Short treatment times (30 and 60 s) did not activate JNK 1/2, while longer times (180 and 360 s) resulted in JNK 1/2 up-regulation. JNK 1 was induced up to 3.5-fold of control after 360 s (p < 0.05, *) of plasma exposure, while JNK 2 showed an up-regulation up to 4.5 for a plasma treatment of 360 s. JNK 1/2 cascade involvement in oxidative stress mediatedapoptosis induction has been reported [30]. Especially long treatments lead to reactive species accumulation in the medium [31].…”

Section: Plasma-mediated Regulation Of Mapk Signaling Pathwaysmentioning

confidence: 86%

“…Immediately after monocyte isolation, plasma treatment was performed indirectly; This means that 5 mL of monocyte culture medium (RPMI 1640 containing 10% FCS, 2 mM L-glutamine and 1% penicillin/streptomycin) was plasma treated for distinct times (15,30,60, 180 or 360 s) and then added to 1 × 10 6 monocytes. Appropriate volumes of sterile distilled water were immediately added to the culture medium to compensate molarity changes caused by evaporation during plasma exposure.…”

Section: Plasma Source and Plasma Treatmentmentioning

confidence: 99%

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Non-thermal plasma treatment induces MAPK signaling in human monocytes

et al. 2014

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Abstract:The application of non-thermal atmospheric pressure plasma raises a hope for the new wound healing strategies. Next to its antibacterial effect it is known to stimulate skin cells. However, monocytes are also needed for the complex process of a wound healing. This study investigates the impact of plasma on the intracellular signaling events in the primary human monocytes. The proliferative MEK-ERK (MAPK/ERK kinase-extracellular signal-regulated kinase) pathway was activated by short plasma treatment times. In contrast, an induction of the apoptotic JNK (c-Jun N-terminal kinase) cascade as well as activation of caspase 3 were observed after long plasma exposure. These findings indicate that monocytes can be differentially stimulated by plasma treatment and may contribute to the proper wound recovery.

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Section: Plasma-mediated Regulation Of Mapk Signaling Pathwaysmentioning

confidence: 86%

Section: Plasma Source and Plasma Treatmentmentioning

confidence: 99%

Non-thermal plasma treatment induces MAPK signaling in human monocytes

et al. 2014

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“…ROS induced by various oxidative stresses including plasma treatments [53] have been shown to induce DNA damage in addition to mitochondrial injury [54,55].…”

Section: Discussionmentioning

confidence: 99%

Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial–nuclear network

Adachi

Tanaka

Nonomura

et al. 2015

Free Radical Biology and Medicine

300

295

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“…The novel NTP system tested was able to significantly reduce E. coil in milk by more than a threefold log reduction without significantly affecting pH or color properties (Gurol et al 2012). Some other scholars have also proved that non-thermal plasma had a significant effect in killing food microbes, such as bacterial, Saccharomyces cerevisiae, spore (Perni et al 2008;Ermolaeva et al 2012;Bayliss et al 2013;Liu et al 2013;Ma et al 2013;Baier et al 2013). An original non-thermal process to inactivate dehydrated (Surowsky et al 2013).…”

Section: Introductionmentioning

confidence: 92%

Effects of non-thermal plasma sterilization on volatile components of tomato juice

Lan

2015

Int. J. Environ. Sci. Technol.

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Pasteurization is an important issue to keep from fruit decay due to microbes for fruit preservation. Conventional heat sterilization is based on thermal process. However, the flavor and nutrition components can be changed by heat damage. In this study, an apparatus was designed to produce non-thermal plasma (NTP), which can be applied in fruit sterilization. NTP can be generated through electric discharge in gaseous chamber. A simple NTP reactor may consist of two electrodes with a chamber and connected to a high-voltage power supply. The new technique of NTP was applied to keep fruit fresh. After the tomatoes were treated by NTP, the volatile flavor components were analyzed by GC-MS and were compared to heat treatment and non-treatment. The results showed that the quality of fresh tomato fruit was unaffected by plasma disinfection treatment, and the contents of trans-2-hexenal and n-hexanal were significantly higher than that by heat processes. NTP has less effect on volatile chemical compositions of tomato juice. NTP technology is a promising method for food pasteurization in the future.

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Atmospheric pressure cold plasma leads to apoptosis in saccharomyces cerevisiae by accumulation of intracellular reactive oxygen species and calcium

Cited by 17 publications

References 0 publications

Non-thermal plasma treatment induces MAPK signaling in human monocytes

Non-thermal plasma treatment induces MAPK signaling in human monocytes

Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial–nuclear network

Effects of non-thermal plasma sterilization on volatile components of tomato juice

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