Atmospheric HULIS and its ability to mediate the reactive oxygen species (ROS): A review

Win, Myat Sandar; Tian, Zhuang; Zhao, Hui; Xiao, Kai; Jiaxian, Peng; Shang, Yu; Wu, Minghong; Xiu, Guangli; Lü, Sihua; Yonemochi, Shinich; Wang, Qingyue

doi:10.1016/j.jes.2017.12.004

Cited by 64 publications

(54 citation statements)

References 115 publications

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“…1 The widespread occurrence of transition metal ions and peroxides has made Fenton reactions ubiquitous; consequently, these reactions sometimes play crucial roles in vivo, [2][3][4][5][6] in natural waters, 7,8 and in the atmosphere. [9][10][11][12][13] For example, it has been evidenced that Fenton reaction is a source of free radicals that directly contributes to oxidative brain damage, a key early feature of Alzheimer's disease. 5 The generation of reactive oxygen species (ROS) by the redox-active transition metal ions in inhalable fine particulate matters (PM) has also been considered to be the major cause of adverse health effects originated from atmospheric pollutions.…”

Section: Introductionmentioning

confidence: 99%

“…5 The generation of reactive oxygen species (ROS) by the redox-active transition metal ions in inhalable fine particulate matters (PM) has also been considered to be the major cause of adverse health effects originated from atmospheric pollutions. 12,13 Due to these biological and environmental significances, it is crucial to understand the mechanisms of the Fenton reaction per se and the subsequent oxidation reactions initiated by the produced ÁOH.…”

Section: Introductionmentioning

confidence: 99%

“…Hence, UV-enhanced Fenton reactions are often utilized to treat water contaminants 17 and considered to widely occur in atmospheric aerosols during the daytime under solar radiation. 13 More recently, it has been reported that Fe(II) and Fe(III) may react with peroxides, O 2 , or other oxidants such as O 3 to form a high-valent oxoiron moiety, Fe = O, in which iron is in the +IV or +V oxidation state, 18,19 and these studies have added to the complexity of Fenton reaction mechanism. The ÁOH generated in Fenton reactions is the most damaging ROS; consequently, it could readily oxidize all biomolecules such as DNA, proteins, and lipids.…”

Section: Introductionmentioning

confidence: 99%

“…Fenton or Fenton‐like reactions involve the H 2 O 2 oxidation of a low‐valent transition metal ion (e.g., Fe(II) or Cu(I)) into its corresponding high‐valent state (Fe(III) or Cu(II)) as well as the generation of hydroxyl radicals (·OH), and the latter can trigger extensive oxidation chemistries 1 . The widespread occurrence of transition metal ions and peroxides has made Fenton reactions ubiquitous; consequently, these reactions sometimes play crucial roles in vivo, 2–6 in natural waters, 7,8 and in the atmosphere 9–13 . For example, it has been evidenced that Fenton reaction is a source of free radicals that directly contributes to oxidative brain damage, a key early feature of Alzheimer's disease 5 .…”

Section: Introductionmentioning

confidence: 99%

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Beyond lipid peroxidation: Distinct mechanisms observed for POPC and POPG oxidation initiated by UV‐enhanced Fenton reactions at the air–water interface

et al. 2020

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Fenton or Fenton-like reactions are ubiquitous in nature, and the hydroxyl radicals (ÁOH) generated in these reactions are accountable for a plethora of oxidation processes both in the environment and in vivo. Among these oxidation reactions, lipid oxidation initiated by ÁOH radicals has long been oversimplified as a peroxidation mechanism, but in reality, it is a highly complicated process that can result in a large variety of products. Using the unique field-induced droplet ionization mass spectrometry (FIDI-MS) methodology that is capable of selective sampling of amphiphilic molecules that reside at the air-water interface, here, we show distinct mechanisms from the ultraviolet (UV)-enhanced Fenton oxidations of two phospholipids, POPC and POPG, even though these two lipids possess the same functional groups that are vulnerable to ÁOH attack. We postulate that it is the different packing densities that determine the permeability of ambient NO molecules into the monolayers, resulting in highly distinct reaction pathways and products. We anticipate that this work will be a wake-up call that the lipid peroxidation mechanism is sometimes taken for granted and that lipid oxidation can be subtly affected by various factors that deserves deeper investigations.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Beyond lipid peroxidation: Distinct mechanisms observed for POPC and POPG oxidation initiated by UV‐enhanced Fenton reactions at the air–water interface

et al. 2020

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“…Specific absorbance can also be considered as an effective indicator of the origin of HULIS in ambient particulate matter (PM) [2]. HULIS might also threaten human health owing to the production of reactive oxygen species (ROS) or via complexation with transition metals (e.g., Fe, Mn, Cu) [3][4][5]. Recently, many studies have focused on the ROS-generation potential of HULIS in PM 2.5 [6,7].…”

Section: Introductionmentioning

confidence: 99%

Chemical and Optical Characteristics and Sources of PM2.5 Humic-Like Substances at Industrial and Suburban Sites in Changzhou, China

Tao

Sun

et al. 2021

Atmosphere

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The chemical and optical properties and sources of atmospheric PM2.5 humic-like substances (HULIS) were investigated from October to December 2016 in both industrial and suburban areas in Changzhou, China, during polluted and fair days. The average PM2.5 concentration in the industrial region was 113.06 (±64.3) μg m−3, higher than 85.27 (±41.56) μg m−3 at the suburban site. The frequency of polluted days was significantly higher in the industrial region. In contrast, the chemical compositions of PM2.5 at the two sampling sites exhibited no statistically significant differences. Rapidly increased secondary inorganic ions (SNA = NH4+ + SO42− + NO3−) concentrations suggested secondary formation played an important role in haze formation. The daily mean concentration of humic-like substance (HULIS) was 1.8–1.9 times that of HULIS-C (the carbon content of HULIS). Our results showed that HULIS accounted for a considerable fraction of PM2.5 (industrial region: 6.3% vs. suburban region: 9.4%). There were no large differences in the mass ratios of HULIS-C/WSOC at the two sites (46% in the industrial region and 52% in the suburban region). On average, suburban HULIS-C constituted 35.1% of organic carbon (OC), higher than that (21.1%) in the industrial region. Based on different MAE (mass absorption efficiency) values under different pollution levels, we can infer that the optical properties of HULIS varied with PM levels. Moreover, our results showed no distinct difference in E2/E3 (the ratio of light absorbance at 250 nm to that at 365 nm) and AAE300–400 (Absorption Angstrom Exponent at 300–400 nm) for HULIS and WSOC. the MAE365 (MAE at 365 nm) value of HULIS-C was different under three PM2.5 levels (low: PM2.5 < 75 μg m−3, moderate: PM2.5 = 75–150 μg m−3, high: PM2.5 > 150 μg m−3), with the highest MAE365 value on polluted days in the industrial region. Strong correlations between HULIS-C and SNA revealed that HULIS might be contributed from secondary formation at both sites. In addition, good correlations between HULIS-C with K+ in the industrial region implied the importance of biomass burning to PM2.5-bound HULIS. Three common sources of HULIS-C (i.e., vehicle emissions, biomass burning, and secondary aerosols) were identified by positive matrix factorization (PMF) for both sites, but the contributions were different, with the largest contribution from biomass burning in the industrial region and secondary sources in the suburban region, respectively. The findings presented here are important in understanding PM2.5 HULIS chemistry and are valuable for future air pollution control measures.

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Stage-, sex- and tissue-related changes in H2O2, glutathione concentration, and glutathione-dependent enzymes activity in Aiolopus thalassinus (Orthoptera: Acrididae) from heavy metal polluted areas

2021

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Atmospheric HULIS and its ability to mediate the reactive oxygen species (ROS): A review

Cited by 64 publications

References 115 publications

Beyond lipid peroxidation: Distinct mechanisms observed for POPC and POPG oxidation initiated by UV‐enhanced Fenton reactions at the air–water interface

Beyond lipid peroxidation: Distinct mechanisms observed for POPC and POPG oxidation initiated by UV‐enhanced Fenton reactions at the air–water interface

Chemical and Optical Characteristics and Sources of PM2.5 Humic-Like Substances at Industrial and Suburban Sites in Changzhou, China

Stage-, sex- and tissue-related changes in H2O2, glutathione concentration, and glutathione-dependent enzymes activity in Aiolopus thalassinus (Orthoptera: Acrididae) from heavy metal polluted areas

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