Atividade antimicrobiana de Leonorus sibiricus L.

Wadt, Nilsa Sumie Yamashita; Ohara, Mitsuko Taba; Sakuda-Kaneko, Telma M.; Bacchi, Elfriede Marianne

doi:10.1590/s0102-695x1996000200004

Cited by 5 publications

(5 citation statements)

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“…G1, treated with the aqueous extract of L. sibiricus, was the experimental group that presented the lowest edema rate, this finding corroborates other study on this plant, in which it was observed that there is a reduction of paw edema in rats induced by carrageenan with the use of a methanolic extract of L. sibiricus (Islam et al, 2005). Plants of the genus Leonurus contain tannins (Wadt et al, 1996), a polyphenol that precipitates proteins from injured tissues, favoring their repair, besides decreasing vascular permeability and wound exudation, promoting tissue repair (Passaretti et al, 2016), this helps to explain the lower exudation observed in G1.…”

Section: Discussionsupporting

confidence: 88%

Healing and local anti-inflammatory activity of the aqueous extract of Leonurus sibiricus L. leaves in an animal model

Silva,

Alencar,

Vieira

et al. 2023

RSD

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This study analyzed the healing and local anti-inflammatory activity of compounds from the aqueous extract of leaves of the plant Leonurus sibiricus L. (rubim) by evaluating the resolution of cutaneous wounds made in Wistar rats. The wounds were treated daily with the extract of L. sibiricus 10% (m/v) in sodium alginate 5% (m/v) to obtain a gel that facilitated its application; sodium alginate 5% (m/v) and Dexpanthenol 42 mg/g were used as negative and positive controls, respectively. The wounds were evaluated daily for appearance (crusting, swelling) and reduction during 21 days. The data were statistically analyzed and the results indicated that the extract of L. sibiricus favored a better healing evolution of the wounds when compared to the positive control, besides presenting less inflammatory exudate. Regarding the time of resolution (closure) of the wounds, no significant difference was observed between the animals treated with the extract of L. sibiricus and the negative control, however, the extract of L. sibiricus favored a more homogeneous healing giving the wound a better visual appearance, which was confirmed by microscopic analysis. These results corroborate the common sense knowledge of the population that uses this plant in relation to the indicated therapy.

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Section: Discussionsupporting

confidence: 88%

Healing and local anti-inflammatory activity of the aqueous extract of Leonurus sibiricus L. leaves in an animal model

Silva,

Alencar,

Vieira

et al. 2023

RSD

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“…[11] The obtained compounds were dissolved in sterile distilled water and then added at different concentrations. Mueller-Hinton agar was used and a loopful of the organisms previously diluted to 10 6 cfu/ml was also used to inoculate the plates which were incubated at 37°C for 24 hours.…”

Section: Antibacterial Activity Of the Extractsmentioning

confidence: 99%

Antibacterial, antioxidant and acute toxicity tests on flavonoids extracted from some medicinal plants

Akroum¹,

Bendjeddou²,

Satta³

et al. 2010

Int J Green Pharm

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Flavonoids are well-known for their many therapeutic and pharmaceutical effects. In this study, we tested the antibacterial activity of 11 flavonoids extracted from some medicinal plants by the agar diffusion method. Then, we measured their antioxidant activity using the DPPH (2,2'-diphenyl-1-picrylhydrazyl) radical assay and we also tested their acute toxicity effect on mice. The results showed that apigenin-7-O-glucoside was more active against the Gram-positive bacteria and quercetin was more active against the Gram-negative ones. Also, quercetin and diosmin showed the best antioxidant activity. Quercetin, apigenin-7-O-glucoside, luteolin-7-O-glucoside and luteolin-3'-O-glucuronide gave the best acute toxicity values. It can be concluded that quercetin was the most interesting compound for all the tested activities. Also, we observed that the presence or the absence of substitutions in flavonoids influenced significantly the results obtained, whereas the substitution type had a low impact.

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“…The minimum inhibitory concentration (MIC) was determined by the macrobroth dilution method (Wadt et al, 1996). The microorganisms suspensions were adjusted to the standard concentration of approximately 1.0 x 10 2 CFU/mL.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Morphoanatomic aspects and phytochemical screening of Plinia edulis (Vell.) Sobral (Myrtaceae)

Ishikawa¹,

Kato²,

Yoshida³

et al. 2008

Rev. Bras. Cienc. Farm.

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Atividade antimicrobiana de Leonorus sibiricus L.

Cited by 5 publications

References 0 publications

Healing and local anti-inflammatory activity of the aqueous extract of Leonurus sibiricus L. leaves in an animal model

Healing and local anti-inflammatory activity of the aqueous extract of Leonurus sibiricus L. leaves in an animal model

Antibacterial, antioxidant and acute toxicity tests on flavonoids extracted from some medicinal plants

Morphoanatomic aspects and phytochemical screening of Plinia edulis (Vell.) Sobral (Myrtaceae)

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