Atividade antifúngica de óleos essenciais sobre espécies de Candida

Abstract

RESUMO:A candidíase apresenta-se como uma infecção fúngica superfi cial ou profunda causada por leveduras pertencentes ao gênero Candida, sendo considerada a principal infecção micótica em ambiente nosocomial. O objetivo do presente estudo foi determinar a concentração inibitória mínima -CIM do óleo essencial de Cinnamomum zeylanicum Blume, Citrus limon Risso, Eucalyptus citriodora HK, Eugenia unifl ora L., Peumus boldus Benth e de Rosmarinus offi cinialis L. sobre cepas de Candida albicans, C. guilliermondii, C. krusei, C. parapsilosis, C. stellatoidea e C. tropicalis. Os ensaios de atividade antifúngica foram realizados através da técnica de difusão em meio sólido. Os óleos essenciais de C. zeylanicum e P. boldus mostraram os mais destacáveis resultados, visto que inibiram o crescimento de 58% das cepas ensaiadas e apresentaram CIM de 4%.Unitermos: Atividade antifúngica, Óleos essenciais, Cândida, leveduras, micoses.ABSTRACT: "Antifungal activity from essential oils on Candida species" Candidiasis occurs as a superfi cial or profound fungal infection caused by yeasts belonging to the Candida genus. This infectious has been considered the main mycotic infection in the nosocomial environment. The aim of this study was to determine the minimum inhibitory concentration -MIC of Cinnamomum zeylanicum Blume, Citrus limon Risso, Eucalyptus citriodora HK, Eugenia unifl ora L., Peumus boldus Benth and Rosmarinus offi cinialis L. essential oils against Candida albicans, C. guilliermondii, C. krusei, C. parapsilosis, C. stellatoidea e C. tropicalis strains. The antifungal activity assays were carried out by solid medium diffusion technique. C. zeylanicum and P. boldus essential oils showed the most prominent results which inhibited the growth of 58% of the assayed yeasts strains and presented MIC of 4%.

Effectiveness of Lippia sidoides Cham. (Verbenaceae) essential oil in inhibiting the growth of Staphylococcus aureus strains isolated from clinical material

“…P. aeruginosa, B. subtilis, S. aureus, E. coli, Streptococcus spp., Trichosporon spp.) also was reported by other researches (Lemos et al, 1990;Laxoste, 1994;Lima et al, 1994;Siani et al, 2000;Pontes, 2002;Costa et al, 2005;Oliveira et al, 2006). The essential oils of Lippia sidoides was active against larvae of Aedes aegypti and Culex quinquefasciatus (Costa et al, 2005).…”

“…Regarding the increasing clinical importance given to nosocomial and community bacterial infections and the progressive development of antimicrobial resistance, a great number of scientifi c researches emphasizing the antibacterial properties of plant products has been carried out (Hernández et al, 2003;Silva-Santos et al, 2004;Duarte et al 2005;Gayoso et al, 2005;Michelin et al, 2005;Lima et al, 2006a;Lima et al, 2006b). Filtrates, infusions, macerated, juices, extracts and cataplasms from plants with medicinal properties have been applied in the treatment of various diseases since antiquity (Annuk et al, 1999;Hernández et al, 2003).…”

MDGC-MS analysis of essential oils from Protium heptaphyllum (Aubl.) and their antifungal activity against Candida specie

“…Marchand is a tree of the Burseraceae family, aromatic, evergreen or semi-deciduous, of humid sandy soil or dry and that reaches 10-20 m in height (Lorenzi & Matos, 2008). These species are widely spread throughout tropical and subtropical regions, mainly in the Amazon Rainforest.…”

“…heptaphyllum is found in the Amazon region and in some Northeastern states, such as Bahia, Ceara, Piaui, as well as in other countries of South America (Colombia, Paraguay, Suriname and Venezuela) (Citó et al 2003;Lorenzi & Matos, 2008). It's recognized by the use of its leaves and bark as hemostatic, healing and anti-inflammatory, being used by the native people also as a nasal decongestant.…”

Anatomia foliar de Corymbia calophylla (Lindl.) K.D.Hill & L.A.S. Johnson, Myrtaceae

“…Esses mesmos autores indicaram que cerca de 70% das plantas pertencentes a essa família têm potencial terapêutico, sendo utilizadas na medicina tradicional em distúrbios gastrointestinais, estados hemorrágicos e doenças infecciosas. Além disso, diversos trabalhos científicos contemporâneos têm respaldado o uso popular de espécimes dos diversos gêneros de Myrtaceae, por meio de diferentes investigações farmacognósticas, relacionadas aos aspectos botânicos (Paula et al, 2008;Donato & Morretes, 2007;Cardoso & Sajo, 2004;Soffiatti & Angyalossy-Alfonso, 1999), fitoquímicos (Wannes et al, 2008;Cole et al, 2007;Hussein et al, 2007;Migliato et al, 2007;Guo & Yang, 2006;Oliveira et al, 2006) e de atividades biológicas (Salvagnini et al, 2008;Biavatti et al, 2007;Kreuger et al, 2007;Medeiros et al, 2007;Oliveira et al, 2007;Serafin et al, 2007;Alves et al, 2006;Amaral et al, 2006;Apel et al, 2006;Barbosa Filho et al, 2006;Bezerra et al, 2006;Gondim et al, 2006;Lima et al 2006).…”