Äthinierungsreaktionen, XXI. Notiz zur Äthinierung von o‐Chinonen

Synthesis and bioactivity evaluation of 3‐hydroxy‐3‐(phenylethynyl)indol‐2‐one analogues

“…The advances in the use of isatin for organic synthesis and a survey of its biological activities are continuously reported [14–16]. In 1963, Ried reported the synthesis of 3‐hydroxy‐3‐(phenyl‐ethynyl)indol‐2‐one for the first time, with a low yield of 28% [17]. But in the following years, there was no further attention paid to the synthesis and its bioactivity.…”