Atherectomy for Infrainguinal Peripheral Artery Disease

Garcia, Lawrence A.; Lyden, Sean P.

doi:10.1583/08-2656.1

Cited by 31 publications

(30 citation statements)

References 61 publications

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“…For larger vessels such as the CFA, there is a question about primary patency after atherectomy, and the ability of the device to be sized sufficiently to fully treat the large vessels. 10 Catheter-based therapy of the CFA has only been described in a few studies to date. In 27 patients with angioplasty and stent implantation in 33 limbs involving the CFA, technical success was achieved in 100% of the cases with a cumulative primary patency of 83% at 3 years.…”

Section: Discussionmentioning

confidence: 99%

Catheter-based therapy of common femoral artery atherosclerotic disease

Paris¹,

White²,

Collins³

et al. 2011

Vasc Med

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The objective of this paper is to describe outcomes of endovascular therapy in patients with symptomatic common femoral artery (CFA) lesions. Symptomatic atherosclerotic disease of the common femoral artery is an uncommon clinical entity, and there is no consensus regarding the suitability of catheter-based therapy. We reviewed the records of 26 consecutive patients treated with catheter-based therapy for symptomatic CFA lesions between 1994 and 2009. Angiographic success and procedure success were obtained in all vessels and in all patients. At 1 year, 100% (16/16) of the claudication patients and 70% (7/10) of the critical limb ischemia (CLI) patients maintained clinical success. The anklebrachial index (ABI) significantly improved from a baseline of 0.47 ± 0.18 to 0.77 ± 0.18 (p < 0.001) after the procedure. At their most recent clinic visit (31 months ± 14 months), clinical success was maintained in 100% of the claudication patients and in 70% (7/10) of the CLI patients. During the follow-up period, femoral vascular access for an unrelated procedure was obtained through the CFA stent. In conclusion, patients with symptomatic CFA atherosclerotic disease obtained excellent clinical outcomes with angioplasty with stenting. We found that angioplasty with stenting of the CFA did not preclude future CFA vascular access. Our data suggest that catheter-based therapies should be considered as an option to open surgery in selected patients with symptomatic CFA disease.

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Section: Discussionmentioning

confidence: 99%

Catheter-based therapy of common femoral artery atherosclerotic disease

Paris¹,

White²,

Collins³

et al. 2011

Vasc Med

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“…Moreover, a recent randomized trial has demonstrated significantly higher primary patency rates of stenting vs. PTA of femoropopliteal artery lesions TASC A and B at 1-year follow up [7]. However, several alternative endovascular options are available, including subintimal angioplasty, cryoplasty, cutting balloon angioplasty, primary as well as adjunctive deployment of self expanding bare nitinol or covered stents, and ablative modalities such as excimer laser and directional plaque excision [3]. The long term results of these techniques are currently unknown.…”

Section: Discussionmentioning

confidence: 99%

“…In fact, external stent compression in this district may cause restenosis and also stent erosion, and finally fracture when it occurs repeatedly [4]. In contrast, atherectomy offers the theoretical advantages of eliminating stretch injury on arterial walls and reducing the rate of restenosis [3]. In addiction, it removes the obstructing atherosclerotic or intimal hyperplastic lesions without the disadvantage of a foreign body such as a stent in the artery [9].…”

Section: Discussionmentioning

confidence: 99%

“…The patient was classified as TASC IIA (Intersociety consensus for the management of PAD IIA) because of the angiographic aspect; hence, the endovascular therapy was the treatment of choice. Although percutaneous angioplasty with stenting represents the recommended strategy for this kind of lesions [3], we performed a rotational atherectomy in order to prevent stenting complications related to this district, such as stent fracture [4].…”

Section: Introductionmentioning

confidence: 99%

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Rotational atherectomy for the treatment of isolated femoral artery traumatic lesion: a case report

Esposito

Serafino

Gargiulo

et al. 2016

Monaldi Arch Chest Dis

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We describe the case of a 50-year-old man with an isolated plaque of the left distal superficial femoral artery (SFA), probably not related to atherosclerosis, but rather to a traumatic event. He was admitted to our hospital because of intermittent claudication. The critical distal SFA stenosis was documented by angiography and the lesion was treated by rotational atherectomy without stent implantation. At 1-year follow up, Doppler Ultrasound scan demonstrated a normal flow pattern of the left SFA and downstream districts in the absence of any complication. Therefore, rotational atherectomy is a safe and effective technique particularly in cases of peripheral arterial disease wherein stent implantation is dangerous.

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“…PAD can be treated with minimally invasive procedures such as percutaneous transluminal angioplasty, stenting, or cutting of the plaque (i.e., atherectomy) [29][30][31]. In more severe cases, surgery may be necessary to graft a transplanted artery to bypass the blockage.…”

Section: Symptoms and Treatment Strategies For Peripheral Artery Diseasementioning

confidence: 99%

Engineering Integrative Stem Cell and Biomaterial Therapies for Peripheral Artery Disease

Balikov

Lee

Boire

et al. 2015

Biosystems &Amp; Biorobotics

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Because of their potential to regenerate tissues and organs, stem cells garner extensive interest worldwide for treating a wide range of degenerative diseases. In numerous efforts, a variety of stem cell formats have been considered for therapeutic purposes to combat such pathologies, one being vascular-related diseases. In particular, the prevalence of peripheral artery disease (PAD) has steadily increased with the growth of the aging population in many first-world countries. Considering this disturbing trend as well as the obesity epidemic and the ballooning population growth in third-world nations, the burden of PAD is expected to increase worldwide to alarming levels in the coming decades. The advent of stem cell treatments could stymie this burden by alleviating the complications and improving upon the less-than-satisfactory outcomes from current standard-of-care surgical/pharmacological interventions for PAD. This chapter reviews the relevant, cutting-edge clinical and animal model research efforts in the field and explores the remaining questions as they pertain to convergence technologies that may provide the potential for stem cells to reverse PAD-induced tissue damage. Harnessing and translating this potential to create more viable and efficacious PAD treatments should be of paramount global and public health concern.

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Atherectomy for Infrainguinal Peripheral Artery Disease

Cited by 31 publications

References 61 publications

Catheter-based therapy of common femoral artery atherosclerotic disease

Catheter-based therapy of common femoral artery atherosclerotic disease

Rotational atherectomy for the treatment of isolated femoral artery traumatic lesion: a case report

Engineering Integrative Stem Cell and Biomaterial Therapies for Peripheral Artery Disease

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