Asymptomatic bacteriuria in pregnancy: prevalence, risk factors and causative organisms

Abstract

Untreated bacteriuria during pregnancy is associated with adverse maternal and perinatal outcomes. It is cost effective to screen for bacteriuria if the prevalence rate is 2% or more. The prevalence rate in this study was 3.6%. 67% of the aetiological agents belonged to the coliform group and balance 33% were staphylococci. All isolates were sensitive to nitrofurantoin. There was no association between bacteriuria and risk factors such as gestational diabetes, past urinary tract infection, multiparity, advanced maternal age, lower education level, advanced gestational age and lower socioeconomic status. Screening of pregnant mothers is reported to be cost effective if the prevalence rates are ≥2%. It is recommended to screen pregnant mothers early in their pregnancy and treat those with significant bacteriuria as this could significantly minimize adverse maternal and foetal outcomes.

Prevalence of asymptomatic bacteriuria in antenatal women attending a tertiary care hospital

“…This may be due to poor hygiene and lack of basic amenities. Similar trend was noted in the study by Lavanya et al, 12 while Perera J et al 30 found no significant association between them.…”

Virulence factors and antibiotic resistance patterns of uropathogenic Escherichia coli

“…The results agree with previous studies done in the country by Mbanga et al (2010) who found that UPEC showed the highest resistance to ampi-cillin (84%) whilst showing a low resistance to nitro-furantoin (16%). Our findings are also similar to previous studies from Mexico City (Molina-Lopez et al, 2011), Sri Lanka (Perera et al, 2012), Nigeria (Okonko et al, 2009) India (Mandal et al, 2012) and Iran (Barati et al, 2011) which found a low resistance to nitrofurantoin and a high resistance to ampicillin. UPEC strains tend to be resistant to drugs that are frequently used.…”

Asymptomatic bacteriuria and antimicrobial susceptibility pattern of the isolates among pregnant women attending Dessie referral hospital, Northeast Ethiopia: A hospital-based cross-sectional study

“…All of these factors bring urinary stasis, dysfunctional ureteric valves and vesico-ureteral reflux, which assists bacterial colonization and rising infection. [5] This environment is suitable to E. coli. The current study also reported high prevalence rate of S.aureus (31.04%).…”

“…All these features lead to urinary stasis, nonfunctional ureteric valves, and vesicoureteral reflux, which facilitate bacterial migration and ascending infection. [5] A recent study showed that both Gram-negative and positive bacteria are predominantly responsible from ASB during pregnancy worldwide. The most commonly implicated bacteria responsible for ASB in pregnant women are Escherichia coli, Proteus spp., Klebsiella spp., Pseudomonas spp., Enterococcus spp., Staphylococcus aureus, and coagulase-negative Staphylococci.…”