“…Sterically hindered ketones (e.g., 4-octanone, tert-butyl methyl ketone, isobutyl isopropyl ketone, or n-amyl phenyl ketone) were not reduced at all. These results27, 28 the substrate is dissolved in a relatively non-toxic, water miscible solvent (e.g. ethanol, acetone, propylene glycol, DMSO, ethylene glycol monomethylether) prior to addition.…”