Baker's yeast mediated transformations in organic chemistry

Csük, René; Glaenzer, B. I.

doi:10.1021/cr00001a004

Cited by 603 publications

(114 citation statements)

References 171 publications

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“…Under the established analytical methods any other compounds were detected in the reaction medium (Table II). In the case of baker's yeast (S. cerevisiae) it has been reported that reductions of acetophenone derivatives produce (S)-alcohols in low to moderate yield and higher enantiomeric excess (Csuk and Glaenzer, 1991). These results indicate that evaluation of the same S. cerevisiae species does not always show the same outcome, since the process depends on parameters like nature of nutrients, substrate concentration, temperature, cell age, pH or additives present in the medium (Fantin et al, 1994;Nakamura et al, 1984).…”

Section: Reduction Of Acetophenone (1)mentioning

confidence: 99%

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Bioreduction of Some Common Carbonylic Compounds Mediated by Yeasts

Silva

Alarcón

Águila

et al. 2010

Zeitschrift Für Naturforschung C

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Bioreduction of several prochiral carbonylic compounds such as acetophenone (1), ethyl acetoacetate (2) and ethyl phenylpropionate (3) to the corresponding optically active secalcohols 1a -3a was performed using wild-type strains of Pichia pastoris UBB 1500, Rhodotorula sp., and Saccharomyces cerevisiae. The reductions showed moderate to excellent conversion and high enantiomeric excess, in an extremely mild and environmentally benign manner in aqueous medium, using glucose as cofactor regeneration system. The obtained alcohols follow Prelog's rule, but in the reduction of 1 with P. pastoris UBB 1500 the antiPrelog enantiopreference was observed.

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Section: Reduction Of Acetophenone (1)mentioning

confidence: 99%

“…3B). It is noteworthy that the enzyme's hydrolytic activity present in the cell can hydrolyze either 3 or 3a into high polar compounds (Csuk and Glaenzer, 1991).…”

Section: Reduction Of Ethyl Phenylpropionate (3)mentioning

confidence: 99%

Bioreduction of Some Common Carbonylic Compounds Mediated by Yeasts

Silva

Alarcón

Águila

et al. 2010

Zeitschrift Für Naturforschung C

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“…The latter of ones is very important on account of the deficit of an organic matter in the soils of Europe. Industrial wastewater (process water) from the yeast production process may by used directly or as a concentrated fertilizer [3,17,23,28,41,46,47]. Technological wastewater from the yeast industry have not only a high pollutants load but are produced in great amounts as well.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Possibility of Yeast Production Increase at Maintained Carbon Dioxide Emission Level

Włodarczyk¹,

Włodarczyk²

2016

Civil and Environmental Engineering Reports

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Main parameters polluting of technological wastewater (dregs from decantation and thicken of the wort) from yeast industry are: nitrogen, potassium and COD. Such wastewater are utilized mostly on agricultural fields. Unfortunately, these fields can only accept a limited amount of wastes. The basic parameter limiting there the amount of wastewater is nitrogen. When capacity of the production is large sewages are often pretreated at an evaporator station. However, due to the fairly high running costs of the evaporator station currently such a solution is applied only to a small amount of wastes (just to meet legal requirements). Replacement of the earth gas with a biomass being supplied to the evaporator station from the agricultural fields will both allow to maintain the carbon dioxide emission level and enable the production growth. Moreover, the biomass growing on the agricultural fields being fertilized with the wastewater coming from the yeast production allows consequently to utilize the greater volume of wastewater. Theoretically, the possible increase in the yeasts production, with maintaining the carbon dioxide emission level, can reach even 70%. Therefore, the solution presented in this paper combines both intensification of the yeasts production and maintaining the carbon dioxide emission level.

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“…In recent years, microorganism whole cells as sources of biocatalysts have widely been used in the laboratory and industry [1]. It is well known the application of baker's yeast oxidoreductases in reduction of carbonyl compounds such as aldehydes, ketones, ketoesters and ketoacids [2][3][4].…”

Section: Introductionmentioning

confidence: 99%