Asupan makan, status gizi, dan kualitas hidup pasien kanker payudara di RSUP DR Sardjito Yogyakarta

Abstract

Background: Breast cancer is the fi fth leading cause of death due to all the type of cancer and the second leading cause of death in developing country after lung cancer. The global incidents of this disease were 43%. The cancer cells have an ability to disturb the nutrients absorbtion in the body and give an effect of decreasing nutritional status, physical performance and quality of life. Objective: To show the relationship between nutrient intake, nutritional status and quality of life, breast cancer patients with radiotherapy at Sardjito Hospital Yogyakarta. Method: This study was an observational study with cross sectional design. Total subject of this study were 85 respondents. Intake of energy, protein, fat and carbohydrate were measured using 1x24 hours food recall. Nutritional status were measured using patient-generated subjective global assessment (PG-SGA) questionnaire. Then the quality of life were measured using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) questionnaire. Results: There were signifi cant difference in the average intake of energy (p=0.013), protein (p=0.043) and fat (p=0.016) between severe malnourished, moderate malnourished and wellnourished patients, whereas the average intake of carbohydrate was not signifi cant (p=0.070). The lower nutrition intake, the lower nutritional status. There was also signifi cant difference in fat intake (p=0.035) and nutritional status based on PG-SGA (p=0.002) between patients with poor and good quality of life. Patients with poor quality of life had lower nutrition intake and nutritional status. Conclusion: Nutrient intake gave an effect to nutritional status and quality of life in breast cancer patient with radiotherapy.KEY WORDS: breast cancer; nutrient intake; nutritional status; quality of life ABSTRAK Latar belakang: Kanker payudara merupakan penyebab kematian nomor lima di antara semua jenis kanker dan nomor kedua penyebab kematian akibat kanker di negara berkembang setelah kanker paru. Tingkat insidensi kanker payudara secara global sebesar 43,3%. Sel kanker dapat mengganggu penyerapan zat gizi sehingga mempengaruhi penurunan status gizi dan berdampak pada performa fi sik serta kualitas hidup. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara asupan makan, status gizi, dan kualitas hidup pasien kanker payudara dengan radioterapi di RSUP Dr. Sardjito Yogyakarta. Metode: Penelitian observasional dengan desain cross sectional dan jumlah subjek penelitian sebesar 85 responden. Asupan energi, protein, lemak, dan karbohidrat diukur menggunakan food recall 1x24 jam. Status gizi diukur menggunakan kuesioner Patient-Generated Subjective Global Assessment (PG-SGA). Kualitas hidup diukur menggunakan kuesioner European Organization for Research and Treatment of Cancer (EORTC QLQ-C30). Hasil: Terdapat perbedaan yang signifi kan rerata asupan energi (p=0,013); protein (p=0,043); dan lemak (p=0,016) antara pasien yang tergolong malnutrisi berat, sedang, dan status gizi baik, sedang...

The Effect of Dietary Modification and Nutritional Education on Nutrition Care Process (NCP) for Increasing Dietary Intake, Body Weight, and Nutritional Status of Cancer Patients at Risk of Malnutrition and Malnourished in the Inpatient of Dharmais Cancer

“…Provision of nutritional the 3 days of observation in the hospital in this study was in line with the fulfillness of the nutritional needs of the respondents. In line with Susetyowati et al [21], it showed that there was a significant relation between food intake and nutritional status. Based on the results of this study, dietary modification and nutritional education on NCP played an important role in helping cancer patients at risk of malnutrition and malnourished for overcoming their nutritional problems related to malnutrition to improve their intake and fulfill their nutritional needs.…”

“…Patient eating intake is a matter of great concern for cancer patients. As in breast cancer patients undergoing radiotherapy, the lower the intake of food is, the more severe the condition of malnutrition will be wherein the intake of food also affects nutritional status and quality of life [21].…”

Ekstrak Etanol Daun Sirsak Tidak Menghambat Pertumbuhan Jaringan Tumor Payudara Tikus Rattus norvegicus Betina galur Sprague-Dawley Akibat Paparan 7,12-Dimethylbenz(α)anthracene dan Estrogen

“…15 Jika penderita underweight, status gizi penderita dapat menurun, sehingga meningkatkan komplikasi pengobatan kanker, 16 antara lain malnutrisi dan kakeksia yang diinduksi tumor. 17 Malnutrisi penderita tumor dapat disebabkan oleh beberapa faktor, yaitu umur, pengetahuan gizi, asupan makanan, infeksi, jenis tumor, dan terapi pengobatan. 17 Kakeksia merupakan kondisi hilangnya massa otot dengan atau tanpa lipolisis yang tidak dapat dipulihkan dengan dukungan nutrisi konvensional.…”

“…17 Malnutrisi penderita tumor dapat disebabkan oleh beberapa faktor, yaitu umur, pengetahuan gizi, asupan makanan, infeksi, jenis tumor, dan terapi pengobatan. 17 Kakeksia merupakan kondisi hilangnya massa otot dengan atau tanpa lipolisis yang tidak dapat dipulihkan dengan dukungan nutrisi konvensional. 18 Kakeksia diinduksi tumor disebabkan oleh anoreksia, hipermetabolisme, adanya proteolysisinducing factor (PIF) dalam serum yang mampu menginduksi secara seimbang degradasi protein dan penghambatan sintesis protein, sehingga menurunkan sintesis protein tubuh dan meningkatkan aktivitas lipolitik melalui aktivasi hormone-sensitive lipase, turunnya efek anti-lipolitik insulin adiposit, sehingga penyerapan lipid sangat terhambat.…”

Hubungan asupan energi dan protein dengan perubahan berat badan dan kekuatan genggam tangan pasien kanker rawat inap di rsup dr. Sardjito

“…Pada penelitian tersebut didapatkan hubungan yang signifikan antara penurunan asupan energi dengan penurunan berat badan setelah 3 minggu pengobatan (14). Penelitian pada pasien kanker payudara di Yogyakarta, pasien kanker nasofaring di Surakarta dan pasien kanker di Surabaya juga menemukan adanya hubungan yang signifikan antara asupan energi dengan status gizi (15,16,17). Kecukupan asupan energi sebesar 75% dapat meminimalisasi penurunan berat badan selama perawatan (10).…”