Asthme et pollution atmosphérique

Mekki, F.; Taktak, S.; Mechaal, S. El; Hamzaoui, A.; Ghedira, Habib

doi:10.1016/s0761-8417(04)72078-7

Cited by 2 publications

(1 citation statement)

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“…Nowadays, the incidence of pulmonary diseases continues to grow, owing largely to atmospheric pollution and environment alterations [ 94 , 95 ]. In respiratory diseases, acute inflammatory reactions and recruitment of immune cells such as neutrophils, monocytes, and macrophages were reported to occur in the lesion areas [ 96 ], followed by production and secretion of large amounts of reactive oxygen species and pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, which may provoke alveolar damage and obstruct gas exchange [ 97 , 98 ].…”

Section: Research Of Nnav and Its Components On Inflammatory And Imentioning

confidence: 99%

Anti-Inflammatory and Immune Regulatory Actions of Naja naja atra Venom

Wang

Qin

2018

Toxins

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Naja naja atra venom (NNAV) is composed of various proteins, peptides, and enzymes with different biological and pharmacological functions. A number of previous studies have reported that NNAV exerts potent analgesic effects on various animal models of pain. The clinical studies using whole venom or active components have confirmed that NNAV is an effective and safe medicine for treatment of chronic pain. Furthermore, recent studies have demonstrated that NNAV has anti-inflammatory and immune regulatory actions in vitro and in vivo. In this review article, we summarize recent studies of NNAV and its components on inflammation and immunity. The main new findings in NNAV research show that it may enhance innate and humoral immune responses while suppressing T lymphocytes-mediated cellular immunity, thus suggesting that NNAV and its active components may have therapeutic values in the treatment of inflammatory and autoimmune diseases.

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