2010
DOI: 10.3109/02770903.2010.538106
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Asthma Symptoms, Lung Function, and Markers of Oxidative Stress and Inflammation in Children Exposed to Oil Refinery Pollution

Abstract: Objectives. Little is known about the effects of exposure to petroleum refinery emissions on respiratory health in children. We evaluated lung function and markers of inflammation and oxidative stress in children and adolescents with and without asthma or wheezing symptoms living in a petrochemical polluted area (Sarroch, Sardinia) versus a reference area (Burcei). Methods. Parents of 275/300 6-to 14-year-old children living in Sarroch and parents of 214/323 children living in Burcei answered a questionnaire o… Show more

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Cited by 66 publications
(52 citation statements)
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“…Epidemiological studies have shown that exposure to PM 2.5 can be linked to increased incidences of lung cancer, morbidity, and cardiopulmonary disease, and therefore fine particles are a growing public health concern (Akyüz and Cabuk, 2009;Pope et al, 2009;Peacock et al, 2011;Raaschou-Nielsen et al, 2011;Rusconi et al, 2011). Organic aerosols (OAs), which typically compose 20-50% of the total fine particulate mass, have been implicated as the cause of detrimental effects on ecosystems, and these particles also play important roles in climate change (Venkataraman et al, 2002;Oanh et al, 2002;Saxena and Hildemann, 1996).…”
Section: Introductionmentioning
confidence: 98%
“…Epidemiological studies have shown that exposure to PM 2.5 can be linked to increased incidences of lung cancer, morbidity, and cardiopulmonary disease, and therefore fine particles are a growing public health concern (Akyüz and Cabuk, 2009;Pope et al, 2009;Peacock et al, 2011;Raaschou-Nielsen et al, 2011;Rusconi et al, 2011). Organic aerosols (OAs), which typically compose 20-50% of the total fine particulate mass, have been implicated as the cause of detrimental effects on ecosystems, and these particles also play important roles in climate change (Venkataraman et al, 2002;Oanh et al, 2002;Saxena and Hildemann, 1996).…”
Section: Introductionmentioning
confidence: 98%
“…Long-term exposure to air pollution PM increases the risk of lung cancer, respiratory diseases and arteriosclerosis, whereas short-term exposure can exacerbate several forms of respiratory diseases, i.e. bronchitis and asthma, and changes in heart rate variability (Dominici et al 2007 ;Peacock et al 2011 ;Pope et al 2009 ;Raaschou-Nielsen et al 2011 ;Rusconi et al 2011 ). However, fundamental uncertainties still exist with respect to the underlying mechanisms of toxicity that are responsible for the mortality or morbidity increases following exposure to current levels of air pollution PM (Schwarze et al 2007 ).…”
Section: Introductionmentioning
confidence: 99%
“…Even low-level chronic exposures to some chemical pollutants have been implicated as contributors to the increase and prevalence of diseases or illnesses such as cancer, negative developmental and birth outcomes, asthma, and neuro-development delay (Boeglin et al 2006;Whitworth et al 2008;Bose-O'Reilly et al 2010;Mattison 2010;Rusconi et al 2010). The economic cost of ill health due to pollution is estimated to be substantial (Jerrett et al 2003;Agarwal et al 2010).…”
Section: Discussionmentioning
confidence: 97%