Asthma and Eczema in Children Born to Women With Migraine

Chen, T. C.; Leviton, Alan

doi:10.1001/archneur.1990.00530110087022

Cited by 54 publications

(38 citation statements)

References 34 publications

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“…In the study population allergy and psychiatric conditions were comorbid with migraine, as reported previously [11][12][13]. In a more detailed analysis the disorders were especially prevalent among the MwA+MwoA, Unc.mig and MwA phenotypes.…”

Section: Discussionsupporting

confidence: 62%

Comorbidity in Finnish migraine families

Artto

Wessman

Nissilä³

et al. 2006

J Headache Pain

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The objective of the study was to investigate comorbidity of migraine in Finnish migraine families. One thousand consecutive participants in the Finnish Migraine Gene Project reported their medical illnesses in addition to migraine and headache. Migraine patients (n=678) reported significantly more hypotension (OR 1.43, CI 95% 1.02-2.01), allergy (OR 1.83, CI 95% 1.34-2.51) and psychiatric disorders (OR 4.09, CI 95% 2.11-7.92) compared to their family members without migraine (n=322). Subgroup analyses demonstrated that especially women and the group fulfilling the criteria for both migraine with and without aura were likely to have additional disorders besides their migraine. Interestingly, male migraineurs with aura reported a significant association with stroke and epilepsy. Familial migraine is comorbid with hypotension, allergy and psychiatric disorders. The association between migraine with aura and stroke and epilepsy among men of the studied families warrants further study. Clinical, pathophysiological and genetic implications of these results are discussed.

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Section: Discussionsupporting

confidence: 62%

Comorbidity in Finnish migraine families

Artto

Wessman

Nissilä³

et al. 2006

J Headache Pain

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“…It was reported that the risk of the development of asthma was higher in children whose parents had migraine [12]. In our study, the relationship between familial histories of asthma, migraine, and allergic symptoms and headache and migraine in asthma patients was significant, and it was recommended to examine the presence of headache and migraine in asthma patients with such a familial anamnesis.…”

Section: Discussionmentioning

confidence: 66%

Presence of Headache and Migraine in Asthma Patients

Turan¹,

Susuz²,

Turan³

2017

Turk Thorac J

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OBJECTIVES:Migraine is a diseases characterized with severe headaches, with neurological and systemic findings. The purpose of this study is to investigate the prevalence of migraine and to examine whether there is a relationship between atopic disorders, parental history and migraine in asthma patients. MATERIAL AND METHODS:A total of 288 asthma outpatients, who had the diagnosis by an early or late test of reversibility showing a reversible airway obstruction according to hospital database were included. The presence of headache, atopic symptoms and parental history about asthma, atopic disorders and migraine were asked. The patients with headache were consultated by neurology department and investigated about the presence of migraine. The diagnosis of migraine headache was made if patients fulfilled the International Headache Society (IHS) criteria. RESULTS:60.4% of patients described a headache. There were 94 patients (32.6%) with headaches meeting the IHS criteria for migraine. Only 12 patients had migraine with aura. There were atopic symptoms in 86.8% of patients. According to parental history, there were asthma in 47.9%, atopic symptoms in 39.6% and migraine in 22.2% of parents. Patients with atopic symptoms were found to have significantly high rate of headaches (65.3%) "p=0.007". The prevalence of migraine was significantly high in patients with parental atopic symptoms (54%) "p=0.002". Multiple logistic regression analysis identified that gender, parental history of asthma, allergia and migraine, and smoking were independent risk factors for presence of migraine in asthmatics. CONCLUSION:There is a high prevalence of migraine headaches in patients with asthma. The coexistence of asthma and headaches may be related with a similar pathophysiological mechanism; parental history, common genetic compounds and smoking may play role in this mechanism. The headaches in asthma patients, atopic symptoms and family history should be questioned, and clinicians should be careful about the presence of migraine.

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“…[68][69][70] Moreover, children born to mothers who have migraine are twice as likely to have asthma or eczema in the first 7 years of life than those born to mothers without migraine or asthma/eczema (6% vs 3.2%). 71 The risk of having asthma/allergies is greater if the mother had both migraine and asthma/eczema. 71 Advances in the pathogenesis of migraine may be germane to the physiology of chemical sensitivity and explain the overlap of symptoms between and genetic predisposition to the two disorders.…”

Section: Odorsmentioning

confidence: 99%

“…71 The risk of having asthma/allergies is greater if the mother had both migraine and asthma/eczema. 71 Advances in the pathogenesis of migraine may be germane to the physiology of chemical sensitivity and explain the overlap of symptoms between and genetic predisposition to the two disorders. Neurogenic (or sterile) inflammation is characterized by edema, vasodilation, and leukocytic infiltration.…”

Section: Odorsmentioning

confidence: 99%

Migraine and the Environment

2009

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Migraineurs often describe environmental triggers of their headaches, such as barometric pressure change, bright sunlight, flickering lights, air quality, and odors. Environmental aspects of indoor space and workplaces are also implicated in migraine experience. Comprehensive migraine treatment programs emphasize awareness and avoidance of trigger factors as part of the therapeutic regimen. As migraine has a substantial economic impact, remediation of correctable environmental triggers may benefit employee attendance and productivity among migraineurs. Few controlled studies in the literature, however, confirm environmental influences on migraine and headaches. Although some are controversial, migraineurs worldwide consistently report similar environmental triggers. This article addresses commonly mentioned environmental triggers with a discussion of their pathophysiology and proposed preventive measures. Objective: To examine the epidemiological evidence for commonly‐mentioned environmental migraine triggers, discuss their possible role in the pathophysiology of migraine and propose preventive measures to avoid or minimize exposure. Background: Migraineurs often describe environmental triggers of their headaches, such as barometric pressure change, bright sunlight, flickering lights, air quality and odors. Environmental aspects of indoor space and workplaces are also implicated in the migraine experience. As migraine has a substantial economic impact, remediation of correctable environmental triggers may improve attendance and productivity among migraineurs in the workplace. Methods: We reviewed the literature addressing indoor and outdoor environmental factors which are commonly implicated as migraine triggers. Results: Although some factors are controversial, migraineurs worldwide consistently report similar environmental triggers. However, few studies confirm environmental influences on migraine and headaches. Research to date indicates that migraineurs have lower thresholds for light‐induced discomfort, sine grating distortion and illusions, noise tolerance and olfactory sensitivity compared to the general population. Conclusion: There are conflicting studies supporting the validity of patient‐reported environmental migraine triggers. Prospective studies are needed to determine the extent that external stimuli influence the migraine process. Decreased thesholds for light, noise, olfactory and visual stimuli in migraineurs may be minimized by modifying the work, home and classroom settings.

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Asthma and Eczema in Children Born to Women With Migraine

Cited by 54 publications

References 34 publications

Comorbidity in Finnish migraine families

Comorbidity in Finnish migraine families

Presence of Headache and Migraine in Asthma Patients

Migraine and the Environment

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