Associations of Vitamin D Intake with 25-Hydroxyvitamin D in Overweight and Racially/Ethnically Diverse US Children

Au, Lauren E.; Rogers, Gail; Harris, Susan S.; Dwyer, Johanna T.; Jacques, Paul F.; Sacheck, Jennifer M.

doi:10.1016/j.jand.2013.05.025

Cited by 34 publications

(32 citation statements)

References 19 publications

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“…Second, consistent with two recent reports [44,45], our population had slightly higher than expected BMI values when compared to age- and sex-referenced normative data. While previous research indicates a positive correlation between body weight and BMD in children [46], it also indicates that obese children have lower levels of 25-hydroxyvitamin D than non-obese children [47], with the potential to compound the adverse effects of treatment for ALL on bone during the course of curative therapy Our findings indicate that early interventions designed to both prevent bone loss and preserve muscle mass are important for children with newly diagnosed ALL.…”

Section: Discussionmentioning

confidence: 62%

Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia

Ness

Kaste

Zhu

et al. 2014

Leukemia & Lymphoma

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This study describes skeletal, neuromuscular and fitness impairments among 109 children (median age 10 (range 4–18) years, 65.1% male, 63.3% white) with acute lymphoblastic leukemia (ALL), enrolled on a physical activity trial from 2009 to 2013. Outcomes were measured 7-10 days after diagnosis and compared to age- and sex-specific expected values. Associations between function and HRQL were evaluated with logistic regression. Children low values for BMD z-scores/height (mean±standard error: −0.53±0.16 vs. 0.00±0.14, p <0.01), body mass index percentile (57.6±3.15 vs. 50.0±3.27%, p=0.02), quadriceps strength (201.9±8.3 vs. 236.1±5.4 Newtons, p<0.01), six minute walk distance (385.0±13.1 vs. 628.2±7.1 meters, p < 0.001), and Bruininks-Oseretsky Test of Motor Proficiency (23±2.5 vs. 50±3.4%, p < 0.001). Quadriceps weakness was associated with a 20.9-fold (95% CI 2.5–173.3) increase in poor physical HRQL. Children with newly diagnosed ALL have weakness and poor endurance and may benefit from early rehabilitation that includes strengthening and aerobic conditioning.

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Section: Discussionmentioning

confidence: 62%

Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia

Ness

Kaste

Zhu

et al. 2014

Leukemia & Lymphoma

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“…6 the mechanism is unclear. 28,30 It has been hypothesized that vitamin D is stored in adipose tissue and not released when needed, or that there may be enhanced uptake and clearance by adipose tissue. 5 Thus, if dietary intake of vitamin D contributes to 25(OH)D blood concentrations, obese children may be more at risk of low vitamin D status.…”

Section: Discussionmentioning

confidence: 99%

Obesity, lifestyle and socio-economic determinants of vitamin D intake: A population-based study of Canadian children

Colapinto

Rossiter

Khan

et al. 2014

Can J Public Health

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OBJECTIVE: Vitamin D intake in childhood is primarily for the prevention of rickets. Inconsistent evidence has associated adequate blood concentrations with a decreased risk of certain health conditions. Further, obese individuals may have lower vitamin D status. The estimated average requirement (EAR) for children recently doubled to 400 IU/day. Our aim was to examine dietary intake of vitamin D in different body mass index (BMI) categories, in addition to assessing determinants. METHODS:Data from two provincial surveys of grade 5 children, including a food frequency questionnaire and measured BMI, were used. Rao-Scott chi-square statistic tested the bivariate association between provinces and adequate dietary vitamin D intake. Key correlates were examined using multilevel logistic regression. RESULTS:Those below the EAR differed between Alberta (78%) and Nova Scotia (81%). Those drinking <2 glasses of milk/day had 0.02 times the odds of meeting the EAR (95% CI: 0.01-0.02) compared to those drinking more. No significant difference was observed for BMI, though those consuming <1 glass of milk/day were more likely to be obese than those consuming ≥2 glasses/day. Income and physical activity were negatively correlated with meeting the EAR. CONCLUSION:Many children did not meet the EAR for vitamin D from dietary sources and milk consumption was an important determinant. Given trends towards a more sedentary lifestyle and limited sun exposure, we recommend prioritizing public health efforts to support dietary vitamin D intake alongside interventions to increase physical activity and reduce sedentary behaviour. Further investigation is required to determine the need for targeted strategies for obese children.

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“…Entretanto, alguns estudos 56,57,58 têm mostrado que tais estimativas de ingestão são difíceis de serem alcançadas apenas com a dieta.…”

Section: Prevenção Da Deficiência De Vitamina Dunclassified

Vitamina D em pediatria

Almeida¹,

Nogueira‐de‐Almeida²,

Ferraz³

2018

Int J Nutrol

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A vitamina D (VD) é uma das vitaminas lipossolúveis. Suas principais fontes na natureza são a dieta e a produção endógena mediada pela exposição à luz solar. Descobertas recentes mostraram que outros órgãos, que não o rim e o fígado, são também capazes de sintetizar a VD metabolicamente ativa (calcitriol). A deficiência de vitamina D (DVD) foi descrita há quase 2.000 anos e é classicamente relacionada às doenças do sistema ósteo-muscular (em especial, raquitismo e osteomalácia). Adicionalmente nos últimos anos, a DVD tem sido associada à desordens que acometem outros sistemas do organismo, como, por exemplo, asma e diabetes. Além disso, tem sido observada uma elevação da prevalência da DVD em todo o mundo, mesmo em países com boas condições de insolação. A forma mais adequada de prevenção da DVD se dá pela suplementação vitamínica já que não há limites seguros para a exposição solar. O tratamento da DVD baseia-se, principalmente, na reposição da vitamina e está indicado nas formas sintomáticas (sintomas ósteo-musculares) da carência. A intoxicação pela VD é rara e observada em lactentes e crianças jovens que ingerem doses elevadas de VD de forma aguda. Este artigo de revisão aborda estas e outras questões a respeito da VD, com ênfase especial às particularidades relacionadas às crianças e aos adolescentes. Palavras-chave:Colecalciferol. Lactente. Vitamina D. ABSTRACTVitamin D (VD) is one of the fat-soluble vitamins. Its main sources in nature are diet and exposure to sunlight. Recent findings have shown that organs other than the kidney and liver are also able to synthesize VD metabolically active (calcitriol). Vitamin D deficiency (VDD) has been described almost 2.000 years ago and is classically related to diseases of the musculoskeletal system (especially rickets and osteomalacia). However, in recent years, VDD has been linked to disorders that affect other systems in the body, such as asthma and diabetes. In addition, an increase in the prevalence of VDD worldwide has been observed, even in countries with good insolation conditions. The most appropriate way to prevent VDD is by vitamin supplementation since there are no safe limits to sun exposure.

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Associations of Vitamin D Intake with 25-Hydroxyvitamin D in Overweight and Racially/Ethnically Diverse US Children

Cited by 34 publications

References 19 publications

Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia

Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia

Obesity, lifestyle and socio-economic determinants of vitamin D intake: A population-based study of Canadian children

Vitamina D em pediatria

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