Associations between self‐reported physical activity, quality of life, and emotional well‐being in men with prostate cancer on active surveillance

Abstract

Objective The relationship between physical activity (PA) and quality of life (QOL) relative to active treatment for prostate cancer (PCa) has been well‐studied; however, little is known about this relationship during active surveillance (AS). Moreover, whether PA is associated with better emotional well‐being (EWB) in men with low‐risk PCa requires further investigation. Accordingly, we examined the association between self‐reported PA and the average change in QOL and EWB over time during AS. Methods A total of 630 men on AS were included in this retrospective, longitudinal study from AS initiation until AS discontinuation. Generalized estimated equations were used to determine the association between self‐reported PA (independent variable) and QOL and EWB (dependent variables) over time, adjusting for participants' age. Results QOL was higher over time in active (trueβ^(95%CI) = 1.14 (0.11, 2.16), P = .029) and highly active participants (trueβ^(95%CI) = 1.62 (0.58, 2.67), P = .002) compared to their inactive counterparts. Highly active participants had 55% greater odds of experiencing high EWB relative to inactive participants (OR (95%CI) = 1.55 (1.11, 2.16), P = .010). In men with low EWB at baseline (median = 3 months after diagnosis), the highest levels of PA (>1000 metabolic equivalent‐minutes per week) were associated with high EWB over time (OR (95%CI) = 2.17 (1.06, 4.46), P = .034). Conclusions These data further support the importance of PA as a supportive care strategy for men on AS. Our findings suggest that engaging in higher volumes of PA post‐diagnosis may be beneficial particularly for men exhibiting low emotional well‐being early on during AS.

What interventions affect the psychosocial burden experienced by prostate cancer patients undergoing active surveillance? A scoping review

“…These findings were confirmed by the retrospective cohort study conducted by Papadopoulos et al [38], which explored the association between self-reported physical activity, QoL, and emotional well-being in a cohort of 630 men. Highly active participants showed significantly higher (p = 0.002) QoL scores.…”

“…Lifestyle interventions and adjustments comprise the final category [30,31,33,34,[37][38][39][40][41]. Physical activity, exercise, and mindfulness seem to directly affect distress, QoL, and uncertainty [30,33,34,38,41].…”

“…After the full-text screening, 12 studies met all criteria and were included in the review [30][31][32][33][34][35][36][37][38][39][40][41]. This included nine quantitative [30-33, 35, 39-41], one qualitative [37], and two mixed method [34,36] papers.…”

“…Eight studies examined the uptake and effects of lifestyle adjustments [30,31,33,34,[37][38][39][40][41]. Most of them focused on diet and food supplements [31,33,34,39,40].…”

The Mediating Effect of Coping Style on Physical Activity and Negative Affect Caused by Public Health Emergencies: Evidence from Chinese College Students

“…The effect of PA has been inquired in different ages of people such as children [35][36][37], adolescents [37][38][39][40], middle-aged people [41,42] and older adults [43][44][45][46]. There have also been studies on different populations, for instance, pregnant women and mothers [47,48], nurses [49], patients [50][51][52][53][54], and people with overweight/obesity [55,56]. Some scholars have also emphasized the benefits of family members exercising together, such as father-daughter [57,58] and mother-child [59].…”