Associations between Eeg Trajectories, Family Income, And Cognitive Abilities Over the First Two Years of Life

Wilkinson, Carol L.; Pierce, Lara J.; Wade, Mark; Nelson, Charles A.

doi:10.2139/ssrn.4340689

Cited by 2 publications

(3 citation statements)

References 32 publications

(43 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, the observed inverse association between income and growth, contrary to prevailing evidence from numerous other studies indicating a positive link between higher income and improved growth and development [40]. This may be because of the fact that almost all the study participants were from the same socioeconomic class, with notably low median income making meaningful impact differences difficult to distinguish.…”

Section: Discussioncontrasting

confidence: 99%

Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy

Cherkos,

LaCourse,

Kinuthia

et al. 2023

Aids

View full text Add to dashboard Cite

Background: Exposure to HIV and antiretroviral therapy (ART) in utero may influence infant growth and development. Most available evidence predates adoption of universal ART (Option B+ ART regimens). In a recent cohort, we compared growth and development in HIV-exposed uninfected (HEU) to HIV-unexposed (HUU) infants. Design: Prospective cohort study: data from Impact of Maternal HIV on Mycobacterium Tuberculosis Infection among Peripartum Women and their Infants (MiTIPS) in Western Kenya. Methods: Women were enrolled during pregnancy. Mother-infant pairs were followed until 24 months postpartum. We used multivariable linear mixed-effects models to compare growth rates (weight-for-age z-score [WAZ] and height-for-age z-score [HAZ]) and multivariable linear regression to compare overall development between HEU and HUU children. Results: About 51.8% (184/355) of the infants were HEU, 3.9% low birthweight (<2.5 kg), and 8.5% preterm (<37 gestational weeks). During pregnancy, all mothers of HEU received ART; 67.9% started ART pre-pregnancy, and 87.3% received 3TC/FTC,TDF,EFV. In longitudinal analyses, HEU children did not differ significantly from HUU in growth or development (p > 0.05 for all). In the combined HEU/HUU cohort, higher maternal education was associated with significantly better growth and development: WAZ (β=0.18 [95% CI:0.01, 0.34]), HAZ (β=0.26 [95% CI:0.04, 0.48], and development (β=0.24 [95% CI:0.02, 0.46]). Breastfeeding was associated with significantly better HAZ (β=0.42 [95% CI:0.19, 0.66]) and development (β=0.31 [95% CI:0.08, 0.53]). Conclusion: HEU children in the setting of universal maternal ART had a similar growth trajectory and development to HUU children. Breastfeeding and maternal education improved children's weight, height, and overall development irrespective of maternal HIV status.

show abstract

Section: Discussioncontrasting

confidence: 99%

Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy

Cherkos,

LaCourse,

Kinuthia

et al. 2023

Aids

View full text Add to dashboard Cite

show abstract

“…In general, the power changed faster in the first months to slow down the change rate in the following ones. This supports the notion of two developmental periods with different developmental slopes in each one as a recent study has shown with the absolute power (Wilkinson et al, 2023).…”

Section: Discussionsupporting

confidence: 89%

“…The developmental trajectories in relative power were like previous experiments with infants: reduction in theta relative power and increment of alpha relative power (e.g., Marshall et al, 2002; Orekhova et al, 2006; Stroganova et al, 1999). However, beta results differed from other studies that have found an augment of absolute power (Wilkinson et al, 2023) but are similar to Tierney et al (2012). One difference is the nature of the power (absolute vs. relative) as well as the range employed (we removed from 21 Hz onwards), which signals the necessity of more fine‐grained measurements to capture infant electrophysiological development (see Section 4.3.…”

Section: Discussioncontrasting

confidence: 69%

Early development of electrophysiological activity: Contribution of periodic and aperiodic components of the EEG signal

et al. 2023

View full text Add to dashboard Cite

Brain function rapidly changes in the first 2 years of life. In the last decades, resting‐state EEG has been widely used to explore those changes. Previous studies have focused on the relative power of the signal in established frequency bands (i.e., theta, alpha, and beta). However, EEG power is a mixture of a 1/f‐like background power (aperiodic) in combination with narrow peaks that appear over that curve (periodic activity, e.g., alpha peak). Therefore, it is possible that relative power captures both, aperiodic and periodic brain activity, contributing to changes in electrophysiological activity observed in infancy. For this reason, we explored the early developmental trajectory of the relative power in theta, alpha, and beta frequency bands from infancy to toddlerhood and compared it with changes in periodic activity in a longitudinal study with three waves at age 6, 9, and 16 to 18 months. Finally, we tested the contribution of periodic activity and aperiodic components of the EEG to age changes in relative power. We found that relative power and periodic activity trajectories differed in this period in all the frequency bands but alpha. Furthermore, aperiodic EEG activity flattened between 6 and 18 months. More importantly, only alpha relative power was exclusively related to periodic activity, whereas aperiodic components of the signal significantly contributed to the relative power of activity in theta and beta bands. Thus, relative power in these frequencies is influenced by developmental changes of the aperiodic activity, which should be considered for future studies.

show abstract

Associations between Eeg Trajectories, Family Income, And Cognitive Abilities Over the First Two Years of Life

Cited by 2 publications

References 32 publications

Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy

Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy

Early development of electrophysiological activity: Contribution of periodic and aperiodic components of the EEG signal

Contact Info

Product

Resources

About