2015
DOI: 10.1093/gerona/glv181
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Association Rules Analysis of Comorbidity and Multimorbidity: The Concord Health and Aging in Men Project

Abstract: Old age is characterized by a complex pattern of multimorbidity and comorbidity. Single disease definitions do not account for the prevalence and complexity of multimorbidity in older people and a new lexicon may be needed to underpin research and health care interventions for older people.

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Cited by 90 publications
(82 citation statements)
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“…We used association rule mining (ARM) to identify the most common single, dyad, and triad combination of comorbid conditions, and to identify which of these combinations were most highly associated with in‐hospital mortality . ARM is a data mining method originally developed for consumer data to find items commonly purchased together in the same transaction, but it has since been applied to a variety of applications in medicine and bioinformatics . The ARM method can also be used to create “association rules” of the form X = > Y, where X is one or more items and Y is a single‐item consequent that X is associated with.…”
Section: Methodsmentioning
confidence: 99%
“…We used association rule mining (ARM) to identify the most common single, dyad, and triad combination of comorbid conditions, and to identify which of these combinations were most highly associated with in‐hospital mortality . ARM is a data mining method originally developed for consumer data to find items commonly purchased together in the same transaction, but it has since been applied to a variety of applications in medicine and bioinformatics . The ARM method can also be used to create “association rules” of the form X = > Y, where X is one or more items and Y is a single‐item consequent that X is associated with.…”
Section: Methodsmentioning
confidence: 99%
“…Widely accepted equations were not developed with these considerations, thus necessitating the examination of predictive equation accuracy. Given that approximately half of patients admitted to the ICU are greater than 65 years of age and the majority of older adults have MCCs [4, 5], these patients are at increased risk of mortality and functional limitations.…”
Section: Age-related Conditions That Affect Reementioning
confidence: 99%
“…Older patients have higher health care utilization, in addition to a greater chance of hospitalization compared to younger adults due to greater number of comorbidities, less physiologic reserve and lower premorbid functioning [2, 3]. Furthermore, the majority of older adults have at least one chronic condition [4, 5], which may lead to greater susceptibility of hospital-acquired infections and other complications that further contributes to decline in function [6]. Malnutrition is also a prevalent issue within the health care setting that can contribute to functional decline [7], yet estimates suggest only half of malnourished patients are recognized and treated [8, 9].…”
Section: Introductionmentioning
confidence: 99%
“…В зарубежных исследо-ваниях 1-4 сопутствующих заболевания выявляли у 70-75% пожилых [15][16][17], в РФ у больных пожилого воз-раста, госпитализированных в гастроэнтерологиче-ские отделения, одновременно диагностировали 5-8 нозологических форм [18]. В целенаправленном по-пуляционном исследовании, проанализировавшем 17 заболеваний, был продемонстрирован сложный пат-терн мультиморбидности и коморбидности в пожилом возрасте, который авторы подразделили на несколько кластеров (сосудистый, метаболический, нейродеге-неративный, ментальный в сочетании с другим кла-стером, и мышечноскелетный в сочетании с другим кла-стером) [17].…”
Section: коморбидностьunclassified
“…В зарубежных исследо-ваниях 1-4 сопутствующих заболевания выявляли у 70-75% пожилых [15][16][17], в РФ у больных пожилого воз-раста, госпитализированных в гастроэнтерологиче-ские отделения, одновременно диагностировали 5-8 нозологических форм [18]. В целенаправленном по-пуляционном исследовании, проанализировавшем 17 заболеваний, был продемонстрирован сложный пат-терн мультиморбидности и коморбидности в пожилом возрасте, который авторы подразделили на несколько кластеров (сосудистый, метаболический, нейродеге-неративный, ментальный в сочетании с другим кла-стером, и мышечноскелетный в сочетании с другим кла-стером) [17]. В свою очередь, хроническая комор-бидность, особенно гипертензия, сахарный диабет (СД), деменция, хроническая обструктивная болезнь лег-ких, сердечная недостаточность, ишемическая болезнь сердца, фибрилляция предсердий, рак и дисфункция щитовидной железы способствуют развитию гериат-рических синдромов (головокружение и высокий риск падений, когнитивные дисфункции, депрессия, анемия, недержание мочи, нарушения сна и др.)…”
Section: коморбидностьunclassified