“…The incidence of Hodgkin's disease and leukxemia was 9 % and 3 % respectively. Muller (1967) reported the association of zoster and malignant disorders in children. Smallpoxvaccination may proveto be a dangerous, indeed fatal, procedure for patients with depressed immunity; vaccinia gangrenosa, disseminated or generalized vaccinia may develop (Rosenbaum et al.…”