Association of the polymorphism in the 5′-noncoding region of the bovine growth hormone receptor gene with meat production traits in Polish Black-and-White cattle

Maj, Andrzej; Oprządek, J.; Dymnicki, E.; Zwierzchowski, L.

doi:10.1016/j.meatsci.2005.09.001

Cited by 18 publications

(13 citation statements)

References 16 publications

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“…; Maj et al . ; Shin & Chung ). The proposed function of Akirins is as a transcription factor required for NF‐κB‐dependent gene expression in Drosophila and mice, and in the regulation of the innate immune response in Drosophila (Goto et al .…”

Section: Genotype and Allele Frequencies Of C*188g>a Snp In The Akirmentioning

confidence: 97%

Association of a single nucleotide polymorphism in the akirin 2 gene with economically important traits in Korean native cattle

Kim

Lee

et al. 2013

Animal Genetics

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The akirin 2 gene, located on chromosome 9 in cattle, was previously reported to be associated with nuclear factor-kappa B (NF-κB), involved in immune reactions and marbling of meat. To determine whether a single nucleotide polymorphism (SNP) in akirin 2 is associated with economically important traits of Korean native cattle, the c.*188G>A SNP DNA marker in the 3'-UTR region of akirin 2 was analyzed for its association with carcass weight, longissimus muscle area and marbling. The c.*188G>A SNP was genotyped by polymerase chain reaction restriction fragment length polymorphism, and the frequency of the AA, AG, and GG genotypes were 6.82%, 71.29% and 21.88% respectively. This SNP was significantly associated with longissimus muscle area (Bonferroni corrected P < 0.05), and marbling score (Bonferroni corrected P < 0.01). These results suggest that the c.*188G>A SNP of akirin 2 might be useful as a DNA marker for longissimus muscle area and marbling scores in Korean native cattle.

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Section: Genotype and Allele Frequencies Of C*188g>a Snp In The Akirmentioning

confidence: 97%

Association of a single nucleotide polymorphism in the akirin 2 gene with economically important traits in Korean native cattle

Kim

Lee

et al. 2013

Animal Genetics

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“…The data from both groups were processed separately. The full list of analysed traits was given in the previous paper (Maj et al, 2006 …”

Section: Animalsmentioning

confidence: 99%

An association of C/T polymorphism in exon 2 of the bovine insulin-like growth factor 2 gene with meat production traits in Polish Holstein-Friesian cattle

Zwierzchowski¹,

Siadkowska²,

Oprządek³

et al. 2010

CZECH J ANIM SCI

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ABSTRACT:The effect of the insulin-like growth factor 2 (IGF2) gene polymorphism -a g.292C>T transition in exon 2 on feed uptake and conversion, growth rates, and meat production traits in Polish HolsteinFriesian cattle was investigated. A total of 291 young bulls were genotyped using restriction fragment length polymorphism (RFLP-BsrI). Animals were slaughtered at the age of 11 or 15 months and carcass traits were examined. At the age of 11 months the association was shown of the CC genotype with higher cold carcass weight, daily gain and meat content (%) in valuable cuts. At 15 months of age the CC genotype bulls showed higher live body weight, whereas those with the CT genotype had more fat in valuable cuts. The TT genotype bulls appeared to consume more feed (dry matter and protein) and used more feed for maintenance and meat production as compared to the CC genotype. The imprinting status of the IGF2 gene was analysed using cDNA sequencing and RFLP-BsrI. In 15-months-old animals and in foetuses older than two months both IGF2 alleles, maternal and paternal, were equally expressed in liver. In a 2-months-old male foetus the IGF2 mRNA was primarily expressed from the paternal allele.

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“…A better knowledge of the molecular mechanism of marbling is important as it may generate new opportunities for more effective MAS, leading to economic benefits to the beef industry ( Yamada et al, 2009 ). Recently, there have been many efforts to improve meat quality following the development of genomics using DNA markers in livestock ( Maj et al, 2006 ; Otto et al, 2007 ; Gill et al, 2010 ).…”

Section: Resultsmentioning

confidence: 99%

Identification of Single Nucleotide Polymorphism Marker and Association Analysis of Marbling Score in <i>Fas</i> Gene of Hanwoo

Kim

Lee

et al. 2015

Asian Australas. J. Anim. Sci

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The Fas (APO-1, TNFRSF6) gene known as a member of the tumor necrosis factor receptor superfamily was selected for DNA marker development in Korean cattle. It is a cell membrane protein and mediates programmed cell death (apoptosis). We discovered single nucleotide polymorphisms (SNPs) within Fas gene in order to develop novel DNA markers related to economical traits at the genomic level. The sequences of whole exon and 1 kb range of both front and back of the gene were determined by direct-sequencing methods using 24 cattle. A total of 55 SNPs were discovered and we selected 31 common polymorphic sites considering their allele frequencies, haplotype-tagging status and linkage disequilibrium (LD) for genotyping in larger-scale subjects. The SNPs were confirmed genotype through the SNaPshot method (n = 274) and were examined for a possible genetic association between Fas polymorphisms and marbling score. So, the SNPs that were identified significant are g.30256G>C, g.31474C>A, g.31940A>G, and g.32982G>A. These results suggest that SNPs of Fas gene were associated with intramuscular fat content of meat quality traits in Korean cattle.

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Association of the polymorphism in the 5′-noncoding region of the bovine growth hormone receptor gene with meat production traits in Polish Black-and-White cattle

Cited by 18 publications

References 16 publications

Association of a single nucleotide polymorphism in the akirin 2 gene with economically important traits in Korean native cattle

Association of a single nucleotide polymorphism in the akirin 2 gene with economically important traits in Korean native cattle

An association of C/T polymorphism in exon 2 of the bovine insulin-like growth factor 2 gene with meat production traits in Polish Holstein-Friesian cattle

Identification of Single Nucleotide Polymorphism Marker and Association Analysis of Marbling Score in <i>Fas</i> Gene of Hanwoo

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