Association of the MIND diet with cognition and risk of Alzheimer's disease

Koch, Manja; Jensen, Majken K.

doi:10.1097/mol.0000000000000304

Cited by 16 publications

(13 citation statements)

References 9 publications

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“…The MIND diet (Mediterranean-DASH Intervention for Neurodegenerative Delay) was developed some years ago by researchers at Rush University Medical Center in Chicago, IL, and Harvard School of Public Health in Boston, MA, as a hybrid of the Mediterranean-DASH diet. The MIND diet is based on 10 brain-healthy foods (leafy green vegetables, other vegetables, nuts, berries, beans, whole grains, fish, poultry, olive oil, and wine) and 5 unhealthy foods (red meats, butter and stick margarines, cheese, pastries and sweets, and fried or fast food), all of which have a strong scientific rationale in the field of nutritional prevention of dementia [72, 73] (see Table 1). Compared to the MeDi, the MIND diet includes a lower consumption of fish, usually 1 serving/week, as does the DASH diet.…”

Section: Mind Diet and Ad Preventionmentioning

confidence: 99%

Nutrients in the Prevention of Alzheimer’s Disease

Cremonini

Caffa

Cea

et al. 2019

Oxidative Medicine and Cellular Longevity

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Alzheimer’s disease (AD) is a disease caused by the complex interaction of multiple mechanisms, some of which are still not fully understood. To date, pharmacological treatments and supplementation of individual nutrients have been poorly effective in terms of the prevention and treatment of AD, while alternative strategies based on multimodal approaches (diet, exercise, and cognitive training) seem to be more promising. In this context, the focus on dietary patterns rather than on single food components could be more useful in preventing or counteracting the pathological processes typical of AD, thanks to the potential synergistic effects of various nutrients (neuronutrients). The aim of this narrative review is to summarize the currently existing preclinical and clinical evidence regarding the Mediterranean diet (MeDi), the Dietary Approaches to Stop Hypertension (DASH) diet, and the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, which are three dietary patterns with well-known anti-inflammatory and antioxidant properties. Recently, they have been related to brain protection and AD prevention, perhaps thanks to their high content of neuroprotective bioactive compounds. Similarly, intermittent fasting (IF) or calorie restriction (CR) is emerging as interesting approaches that seem to promote hippocampal neurogenesis, activate adaptive stress response systems, and enhance neuronal plasticity, thus leading to motor and cognitive improvements in animal models of AD and hopefully also in human beings.

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Section: Mind Diet and Ad Preventionmentioning

confidence: 99%

Nutrients in the Prevention of Alzheimer’s Disease

Cremonini

Caffa

Cea

et al. 2019

Oxidative Medicine and Cellular Longevity

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“…An observational study that combined two dietary plans including the MedDi and DASH diets called Mediterranean-DASH diet Intervention for Neurological Delay (MIND) diet (fifteen dietary components make up the MIND diet [64]), observed a 53% reduction in the rate of AD [65] and suggested that the MIND diet substantially slows cognitive decline with age [66,67]. Generally, the MIND diet differs from the MedDi by allocating separate categories for green leafy vegetables and berries, and a category for cakes and pastries.…”

Section: Promising Dietary Patterns Associated With the Preventionmentioning

confidence: 99%

Mediterranean and MIND Diets Containing Olive Biophenols Reduces the Prevalence of Alzheimer’s Disease

Omar

2019

IJMS

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The risk of Alzheimer’s disease (AD) increases with nonmodifiable conditions including age and lack of effective efficacious pharmacotherapy. During the past decades, the non-pharmacotherapy mode of treatment of dietary modification received extensive attention in AD research. In order to reduce the AD pathology and cognitive decline, various dietary patterns have been attempted including caloric restriction (CR), dietary approaches to stop hypertension (DASH), ketogenic diets (KD), Mediterranean diet (MedDi) and Mediterranean-DASH diet Intervention for Neurological Delay (MIND) diet. Higher adherence to the MedDi diet was associated with decreases in cardiovascular and neurological disorders including AD and related cognitive decline. However, another emerging healthy dietary pattern MIND diet has also been associated with slower rates of cognitive decline and significant reduction of AD rate. Olive serves as one of the building block components of MedDi and MIND diets and the exerted potential health beneficial might be suggested due to the presence of its bioactive constituents such as oleic acids and phenolic compounds (biophenols). A few trials using medical food showed an optimal result in presymptomatic or early stages of AD. The review supports the notion that MedDi and MIND diets display potential for maintaining the cognitive function as nonpharmacological agents against AD pathology and proposed preventative mechanism through the presence of olive biophenols and presents the gaps along with the future directions.

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“…The MIND patterns originated as a combination of the DASH and MedDiet to create a diet that would reduce the risk of dementia and slow down the neurodegeneration process, especially Alzheimer's disease (Moris, 2016). It includes the 10 brain-healthy food groups (green leafy vegetables, other vegetables, nuts, berries, beans, whole grains, seafood, poultry, olive oil, and wine) and the five unhealthy food groups (red meats, butter and stick margarine, cheese, pastries, and sweets, and fried/fast food), all of which prove to be connected with the prevention against dementia (Koch and Jensen, 2016;Cremonini et al, 2019). In comparison with the former dietary patterns, the MIND diet specifies green leafy vegetables and berries and relevant amounts of food components (Moris, 2016).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Healthy Diet on Cognitive Performance Among Healthy Seniors – A Mini Review

Klímová

Dziuba

Cierniak–Emerych

2020

Front. Hum. Neurosci.

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At present, a healthy diet appears to be one of the suitable strategies in slowing down cognitive decline in the process of aging. A number of evidence-based studies confirm its efficacy, safety, and cost-effectiveness. The aim of this mini review is to evaluate and describe recent randomized clinical and cohort studies exploring the effect of healthy diet on cognitive performance among healthy seniors, as well as to update the existing information on this research issue. For these reasons, the authors reviewed full-text, peer-reviewed journal articles written in English and available in Web of Science and PubMed between September 2017 and February 2020. Altogether nine original studies were detected. The results indicate that healthy diet and healthy diet components generally have a positive impact on the enhancement of cognitive functions. Furthermore, the findings reveal that dietary patterns, as well as single nutrients might have a significant effect on specific cognitive domains, such as memory in general, episodic memory, or processing speed. It also seems that a strict adherence to the dietary patterns and a higher diet variety have a more significant effect on the improvement of cognitive functions. Nevertheless, there seem to be gender differences in dietary behavior. More recently, personalized dietary interventions started to be used in delaying cognitive decline among healthy seniors. Therefore, more randomized control trials or N-of-1 trials should be performed in this research area in order to detect the most suitable dietary pattern or nutrients, which would, together with other modifiable lifestyle factors, contribute to the improvement of quality of life of the aging population.

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Association of the MIND diet with cognition and risk of Alzheimer's disease

Cited by 16 publications

References 9 publications

Nutrients in the Prevention of Alzheimer’s Disease

Nutrients in the Prevention of Alzheimer’s Disease

Mediterranean and MIND Diets Containing Olive Biophenols Reduces the Prevalence of Alzheimer’s Disease

The Effect of Healthy Diet on Cognitive Performance Among Healthy Seniors – A Mini Review

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