2014
DOI: 10.1007/s11033-014-3658-8
|View full text |Cite
|
Sign up to set email alerts
|

Association of resistin polymorphisms with resistin levels and lipid profile in children

Abstract: Previous research has found a correlation between resistin and lipid level variations. Polymorphisms in the resistin gene (RETN) could be involved in this relationship, but the results of the different studies are contradictory. The aim of this study was to examine the association between resistin and lipid levels, and to determine whether resistin polymorphisms are associated with resistin levels and lipid profile in prepubertal children and adolescents. The single nucleotide polymorphisms (SNPs) rs1862513 an… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

1
10
1

Year Published

2015
2015
2023
2023

Publication Types

Select...
7
1
1

Relationship

0
9

Authors

Journals

citations
Cited by 14 publications
(12 citation statements)
references
References 36 publications
1
10
1
Order By: Relevance
“…Some studies have confirmed the relationship between rs1862513 SNP, an expression of inflammatory molecules, and adipokines [10,11,35]. Our results did not show any association between basal or post-treatment adipokine serum levels and this RETN variant.…”
Section: Discussioncontrasting
confidence: 45%
“…Some studies have confirmed the relationship between rs1862513 SNP, an expression of inflammatory molecules, and adipokines [10,11,35]. Our results did not show any association between basal or post-treatment adipokine serum levels and this RETN variant.…”
Section: Discussioncontrasting
confidence: 45%
“…However, in contrast to Ukkola et al and Qi et al, they found the relation with serum resistin concentrations to be inverse for the alleles [77,85,89]. A relationship between rs10401670 and serum resistin levels could be detected in 6-to 8-year-old boys ( Table 1) [90].…”
Section: Resistin (Retn)mentioning
confidence: 65%
“…Hivert et al found that the SNP rs10401670 was associated with serum resistin and fasting plasma glucose levels [15]. Similarly, a study of 1269 children by Ortega et al revealed that the SNP rs10401670 was not only associated with resistin levels, but also related to TC and low-density lipoprotein [14]. These results reveal that rs10401670 is closed related to human metabolism.…”
Section: Resistin May Mediate Tumor Initiation and Progression In A Vmentioning
confidence: 95%
“…Resistin, an adipokine that consists of 108 amino acids with a molecular weight of 12.5 kDa, is mainly secreted by monocytes and macrophages [12]. Since the discovery of resistin in 2001, research has focused on its role in obesity, lipid metabolism, and diabetes [13][14][15]. Latest studies indicate that resistin functions in tumor development across multiple systems.…”
Section: Introductionmentioning
confidence: 99%