Association of outdoor air pollution and indoor renovation with early childhood ear infection in China

Deng, Qihong; Lu, Chan; Jiang, Wei; Zhao, Jinping; Deng, Linjing; Xiang, Yuguang

doi:10.1016/j.chemosphere.2016.11.079

Cited by 37 publications

(24 citation statements)

References 69 publications

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“…However, not only in low income countries, wood heaters or fire places are also common in some developed countries. Studies have shown that the results of increased exposure to wood smoke and OM risk are consistent with the toxicological effects of wood smoke on respiratory epithelial cells [28,29]. In the experimental study, the composition of wood smoke increased oxidative stress in epithelial cells [30].…”

Section: Biological Mechanism Of Asomsupporting

confidence: 55%

Analysis of the Association between environmental-meteorological factors and Acute Suppurative Otitis Media: Further Epidemiological Evidence from Lanzhou, Northwestern China

Wang¹,

Xu²,

Tian³

et al. 2020

Preprint

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Objective To investigate the possible associations, lag effects and pathogenic characteristics of urban air quality on acute suppurative otitis media (ASOM）in Lanzhou, a city in Northwestern China. Methods SPSS software was used to analyze Spearman correlation between ambient environment-meteorological factors and the daily number of patient ASOM visits. The GAM of time series was used to analyze the exposure -response curve, and R software was used to calculate RR.Using above results to discuss the relationship of air pollutions , meteorological factors and morbidity of ASOM. Results The number of patients with ASOM in 2014, 2015 and 2016 were 916, 875 and 1023 respectively. There was no significant difference in three years (P=0.85). The annual visits peaked in December, the lowest in August, followed by February, Summer was less than the other three seasons. The morbidity of ASOM had a largest peak within 14 years old (53.84%), and the number of male patients 1514 (53.6%) is 1.16 times that of female patients 1309 (46.4%). Spearman correlation analysis showed that the correlation between air pollutions and environmental variables. As for single-day lag effects , there were positive correlations between PM 2.5 , PM 10 , CO, NO 2 , SO 2 and the daily number of ASOM visits, but the correlation between O 3 and ASOM did not pass the significance test . As for multi-day lag effects, PM 2.5 , PM 10 , CO, NO 2 had lagging effects on the daily number of ASOM visits, but the correlation between SO 2 and O 3 did not pass the significant test. There was a positive correlation between ATM and the daily number of patient ASOM visits, and negative correlation between T and the daily number of patient ASOM visits ,while the correlation between W, RH and ASOM was weak. Conclusions The incidence of ASOM has obvious age and seasonal characteristics. There may be some correlation between environmental-meteorological factors and the incidence of ASOM. Therefore, it is of great significance to strengthen environmental control and public health strategy in order to reduce and prevent the occurrence of ASOM diseases.

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Section: Biological Mechanism Of Asomsupporting

confidence: 55%

Analysis of the Association between environmental-meteorological factors and Acute Suppurative Otitis Media: Further Epidemiological Evidence from Lanzhou, Northwestern China

Wang¹,

Xu²,

Tian³

et al. 2020

Preprint

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“…All the birth cohorts were from either Europe or North America [ 13 , 23 , 24 , 25 , 26 , 27 , 28 ]. The remaining two cohort papers were from a retrospective study of Chinese kindergarten children [ 29 ]. The two case control studies were from the United States and Mozambique [ 30 , 31 ].…”

Section: Resultsmentioning

confidence: 99%

Air Pollution and Otitis Media in Children: A Systematic Review of Literature

Bowatte

Tham

Perret

et al. 2018

IJERPH

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Young children are particularly vulnerable to otitis media (OM) which globally affects over 80% of children below the age of 3 years. Although there is convincing evidence for an association between environmental tobacco smoke exposure and OM in children, the relationship with ambient air pollution is not clear. We aimed to systematically review the literature on the relationship between ambient air pollution exposure and OM in children. A systematic search was performed in PubMed and EMBASE databases. Of 934 references identified, 24 articles were included. There is an increasing body of evidence supporting an association between higher ambient air pollution exposure and a higher risk of OM in children. While NO2 showed the most consistent association with OM, other specific pollutants showed inconsistent associations. Studies were mainly conducted in high/middle income countries with limited evidence from low-income countries. Although there was a general consensus that higher air pollution exposure is associated with a greater prevalence of OM, the evidence for associations with specific pollutants is inconsistent. More well-designed studies on associations between specific air pollutants as risk factors for OM are warranted, especially in low income countries with high air pollution levels.

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“…The China, Child, Homes, Health project conducted a cross-sectional questionnaire survey to examine the associations between in-house environmental factors and the prevalence of asthma and allergies among children aged 3–6 [ 37 ]. Deng et al [ 38 , 39 ] reported that both prenatal and early postnatal exposure to various indoor environmental factors correlated with preschool children suffering from asthma, allergy and various infections. The findings of Liu et al [ 40 ] indicated that culturable fungi and particle concentrations showed strong positive correlations with preschool children’s respiratory health.…”

Section: Introductionmentioning

confidence: 99%

Investigation on Indoor Air Pollution and Childhood Allergies in Households in Six Chinese Cities by Subjective Survey and Field Measurements

et al. 2017

IJERPH

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Greater attention is currently being paid to the relationship between indoor environment and childhood allergies, however, the lack of reliable data and the disparity among different areas hinders reliable assessment of the relationship. This study focuses on the effect of indoor pollution on Chinese schoolchildren and the relationship between specific household and health problems suffered. The epidemiological questionnaire survey and the field measurement of the indoor thermal environment and primary air pollutants including CO2, fine particulate matter (PM2.5), chemical pollutants and fungi were performed in six Chinese cities. A total of 912 questionnaires were eligible for statistical analyses and sixty houses with schoolchildren aged 9–12 were selected for field investigation. Compared with Chinese national standards, inappropriate indoor relative humidity (<30% or >70%), CO2 concentration exceeding 1000 ppm and high PM2.5 levels were found in some monitored houses. Di(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) were the most frequently detected semi-volatile organic compounds (SVOCs) in house dust. Cladosporium, Aspergillus and Penicillium were detected in both indoor air and house dust. This study indicates that a thermal environment with CO2 exceeding 1000 ppm, DEHP and DBP exceeding 1000 μg/g, and high level of PM2.5, Cladosporium, Aspergillus and Penicillium increases the risk of children’s allergies.

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Association of outdoor air pollution and indoor renovation with early childhood ear infection in China

Cited by 37 publications

References 69 publications

Analysis of the Association between environmental-meteorological factors and Acute Suppurative Otitis Media: Further Epidemiological Evidence from Lanzhou, Northwestern China

Analysis of the Association between environmental-meteorological factors and Acute Suppurative Otitis Media: Further Epidemiological Evidence from Lanzhou, Northwestern China

Air Pollution and Otitis Media in Children: A Systematic Review of Literature

Investigation on Indoor Air Pollution and Childhood Allergies in Households in Six Chinese Cities by Subjective Survey and Field Measurements

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