To investigate the correlation between environmental-meteorological factors and daily visits for acute otitis media (AOM) in Lanzhou, China. Methods Data were collected in 2014–2016 by the Departments of Otolaryngology-Head and Neck Surgery at two hospitals in Lanzhou. Relevant information, including age, sex and visiting time, was collected. Environmental data included air quality index, PM10, PM2.5, O 3 , CO, NO 2 and SO 2 , and meteorological data included daily average temperature (T, °C), daily mean atmospheric pressure (AP, hPa), daily average relative humidity (RH, %) and daily mean wind speed (W, m/s). The SPSS22.0 software was used to generate Spearman correlation coefficients in descriptive statistical analysis, and the R3.5.0 software was used to calculate relative risk (RR) and to obtain exposure-response curves. The relationship between meteorological-environmental parameters and daily AOM visits was summarized. Results Correlations were identified between daily AOM visits and CO, O 3 , SO 2 , CO, NO 2 , PM2.5 and PM10 levels. NO 2 , SO 2 , CO, AP, RH and T levels significantly correlated with daily AOM visits with a lag exposure-response pattern. The effects of CO, NO 2 , SO 2 and AP on daily AOM visits were significantly stronger compared to other factors (P < 0.01). O 3 , W, T and RH were negatively correlated with daily AOM visits. The highest RR lagged by 3–4 days. Conclusions The number of daily AOM visits appeared to be correlated with short-term exposure to mixed air pollutants and meteorological factors from 2014 through 2016 in Lanzhou.

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A one-year-old baby girl with one-month history of recurrent pus fluid exuding from her left preauricular sinus orifice, who failed multiple courses of surgical drainage of the abscess and persistent debridement for the wound, presented with MRSA infection. The patient was treated with linezolid for three days. Her pain and paresthesia resolved, and C-reactive protein decreased to normal.

Objective To investigate the possible associations, lag effects and pathogenic characteristics of urban air quality on acute suppurative otitis media (ASOM）in Lanzhou, a city in Northwestern China. Methods SPSS software was used to analyze Spearman correlation between ambient environment-meteorological factors and the daily number of patient ASOM visits. The GAM of time series was used to analyze the exposure -response curve, and R software was used to calculate RR.Using above results to discuss the relationship of air pollutions , meteorological factors and morbidity of ASOM. Results The number of patients with ASOM in 2014, 2015 and 2016 were 916, 875 and 1023 respectively. There was no significant difference in three years (P=0.85). The annual visits peaked in December, the lowest in August, followed by February, Summer was less than the other three seasons. The morbidity of ASOM had a largest peak within 14 years old (53.84%), and the number of male patients 1514 (53.6%) is 1.16 times that of female patients 1309 (46.4%). Spearman correlation analysis showed that the correlation between air pollutions and environmental variables. As for single-day lag effects , there were positive correlations between PM 2.5 , PM 10 , CO, NO 2 , SO 2 and the daily number of ASOM visits, but the correlation between O 3 and ASOM did not pass the significance test . As for multi-day lag effects, PM 2.5 , PM 10 , CO, NO 2 had lagging effects on the daily number of ASOM visits, but the correlation between SO 2 and O 3 did not pass the significant test. There was a positive correlation between ATM and the daily number of patient ASOM visits, and negative correlation between T and the daily number of patient ASOM visits ,while the correlation between W, RH and ASOM was weak. Conclusions The incidence of ASOM has obvious age and seasonal characteristics. There may be some correlation between environmental-meteorological factors and the incidence of ASOM. Therefore, it is of great significance to strengthen environmental control and public health strategy in order to reduce and prevent the occurrence of ASOM diseases.