Association of mate tea (Ilex paraguariensis) intake and dietary intervention and effects on oxidative stress biomarkers of dyslipidemic subjects

Boaventura, Brunna Cristina Bremer; Pietro, Patrícia Faria Di; Stefanuto, Aliny; Klein, Graziela Alessandra; Morais, Elayne Cristina de; Andrade, Fernanda de; Wazlawik, Elisabeth; Silva, Edson Luiz da

doi:10.1016/j.nut.2011.10.017

Cited by 71 publications

(52 citation statements)

References 41 publications

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“…Therefore, it is a key target organ to study the potential biological effects of dietary antioxidants. This, together with the fact that yerba mate has been associated with hepatoprotective, choleretic or anti-inflammatory properties, among others (Boaventura et al, 2012;Bracesco et al, 2011) justifies the study of the potential effects of the phenolic compounds in mate. To this aim, human hepatoma HepG2 cells have been used as a validated model of the human liver that has been widely used in biochemical and nutritional studies to gain insight into the specific mechanisms involved in the biological activity of dietary compounds (Brandon et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

“…Animal studies have shown the anti-obesity effect of mate (Arçari et al, 2009), reducing metabolic and inflammatory markers in high-fat fed obese animals (Pimentel et al, 2013). Mate inhibits plasma and lipoprotein oxidation and can reduce plasma levels of oxidative stress biomarkers in humans (Boaventura et al, 2012), decreasing H 2 O 2 -induced DNA strand break and improving DNA repair in liver cells from mice fed with mate (Miranda et al, 2008). Tamura et al (2013) confirmed a protective effect of yerba mate against alcohol fibrosis and cirrhosis in rat liver modulating cell viability, lipid oxidation and ROS generation through inhibition of cytochrome p450 2E1.…”

Section: Introductionmentioning

confidence: 99%

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Dihydrocaffeic acid, a major microbial metabolite of chlorogenic acids, shows similar protective effect than a yerba mate phenolic extract against oxidative stress in HepG2 cells

Baeza

Sarriá

Mateos

et al. 2016

Food Research International

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dihydrocaffeic acid, a major microbial metabolite of chlorogenic acids, shows similar protective effect than a yerba mate phenolic extract against oxidative stress in HepG2 cells

Baeza

Sarriá

Mateos

et al. 2016

Food Research International

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“…8) Recently published evidence has shown some beneficial effects of Mate, including antioxidant, 9) antiinflammatory, 10) antiobesity, 11) antihyperlipidemic, 12) and antidiabetic properties. 13) To our knowledge, based on pain-related experimental evidence, little is known about the potential analgesic effects of Mate.…”

Section: -7)mentioning

confidence: 99%

Analgesic Effect of <i>Ilex paraguariensis</i> Extract on Postoperative and Neuropathic Pain in Rats

Lim

Kim

Han

et al. 2015

Biological & Pharmaceutical Bulletin

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Ilex paraguariensis, known as "Yerba Mate," is an herb used in a beverage that is widely consumed in southern Latin American countries. Furthermore, it has been traditionally used to treat depression, and as an analgesic to manage both nerve pain and headache. The pain-related experimental evidence regarding the analgesic effects of Mate is unclear. Therefore, this study was designed to investigate whether Mate extract exhibits analgesic effects in both the plantar incision and spared nerve injury (SNI) models in rats. We tested the mechanical withdrawal threshold (MWT) using von Frey filaments. We also tested pain-related behavior using ultrasonic vocalization (USV). Neuropeptide Y (NPY) and pain-related cytokines were also determined in the dorsal root ganglia in a rat model of SNI. Our results showed that oral administration of Mate extract significantly increased MWT values, and reduced the number of 22-27 kHz USVs 24 h after the plantar incision operation. Moreover, after 15 d of continuous treatment with Mate extract, the SNI-induced hypersensitivity, cytokine levels, and NPY expression were significantly reduced compared to the corresponding findings in the control group. These results suggest that the intake of Mate extract has potential as a treatment for both postoperative pain and neuropathic pain.

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“…It is sold in many countries, aside from South America and the United States, as tea products and food supplements, and no side effects have been reported after its ingestion. 18,19 No reports of toxicity or side effects were found while searching the safety databases for data regarding the safety of 'Maté'…”

Section: Discussionmentioning

confidence: 99%

The Effect of Maté Extract on Body Weight and Fat Reduction in Obese Women: A Randomized Placebo-controlled Clinical Trial

Jung

Hur

2016

KJO

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Background: This study was performed to investigate the effects of Maté extract on body weight and fat content in obese women [25.0 kg/m 2 ≤ body mass index (BMI) < 30 kg/m 2 ] aged 20-65 years after 6 weeks of its administration. Methods: The randomized, double-blind, placebo-controlled study was conducted in 33 women. Participants took the supplement, either 2 Maté tablets or 2 placebo tablets, twice daily before meals for 6 weeks. Body weight, body mass index (BMI), waist circumference (WC), and various safety parameters were monitored. Body composition was measured by dual-energy X-ray absorptiometry at baseline and after 6 weeks. Results: Average body weight and BMI did not show any significant changes; however, trunk fat percentage significantly decreased in the Maté group compared to that in the placebo group (-1.24% vs -0.16%, P= 0.03). In the Maté group, the body fat percentages showed a tendency to decrease. All safety parameters were within normal ranges in both groups. Two participants, one from each group, reported nausea during the study. Conclusion: Maté extract significantly reduced trunk fat in obese women after 6 weeks, which indicates that it could improve abdominal fat mass. Furthermore, the supplement is safe and well tolerated.

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Association of mate tea (Ilex paraguariensis) intake and dietary intervention and effects on oxidative stress biomarkers of dyslipidemic subjects

Cited by 71 publications

References 41 publications

Dihydrocaffeic acid, a major microbial metabolite of chlorogenic acids, shows similar protective effect than a yerba mate phenolic extract against oxidative stress in HepG2 cells

Dihydrocaffeic acid, a major microbial metabolite of chlorogenic acids, shows similar protective effect than a yerba mate phenolic extract against oxidative stress in HepG2 cells

Analgesic Effect of <i>Ilex paraguariensis</i> Extract on Postoperative and Neuropathic Pain in Rats

The Effect of Maté Extract on Body Weight and Fat Reduction in Obese Women: A Randomized Placebo-controlled Clinical Trial

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