Association of Feature-Tracking Cardiac Magnetic Resonance Imaging Left Ventricular Global Longitudinal Strain With All-Cause Mortality in Patients With Reduced Left Ventricular Ejection Fraction

Romano, Simone; Judd, Robert M.; Kim, Raymond J.; Kim, Han W.; Klem, Igor; Heitner, John F.; Shah, Dipan J.; Jue, Jennifer; White, Brent E.; Shenoy, Chetan; Farzaneh‐Far, Afshin

doi:10.1161/circulationaha.117.027740

Cited by 50 publications

(33 citation statements)

References 5 publications

(6 reference statements)

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“…Recent evidence suggests that LV global longitudinal strain (GLS) measured with feature-tracking CMR may also identify early LV dysfunction. Romano et al ( 33 ) demonstrated that CMR-derived GLS was a strong, independent predictor of all-cause mortality in those with ischemic and nonischemic dilated cardiomyopathy after accounting for both LVEF and late gadolinium enhancement (LGE) burden. Recent work by Jolly et al ( 34 ) used short-axis cine imaging to measure 3-month serial changes in global LV circumferential strain with feature tracking in 72 patients under-going chemotherapy using automated segmentation ( 34 ).…”

Section: Dysfunctionmentioning

confidence: 99%

Cardiovascular Magnetic Resonance in the Oncology Patient

Jordan

Todd

Vasu

et al. 2018

JACC: Cardiovascular Imaging

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Patients with or receiving potentially cardiotoxic treatment for cancer are susceptible to developing decrements in left ventricular mass, diastolic function, or systolic function. They may also experience valvular heart disease, pericardial disease, or intracardiac masses. Cardiovascular magnetic resonance may be used to assess cardiac anatomy, structure, and function and to characterize myocardial tissue. This combination of features facilitates the diagnosis and management of disease processes in patients with or those who have survived cancer. This report outlines and describes prior research involving cardiovascular magnetic resonance for assessing cardiovascular disease in patients with or previously having received treatment for cancer.

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Section: Dysfunctionmentioning

confidence: 99%

Cardiovascular Magnetic Resonance in the Oncology Patient

Jordan

Todd

Vasu

et al. 2018

JACC: Cardiovascular Imaging

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“…Finally, we speculate that the presence of reduced strain values in CA-LVEF p might have independent prognostic importance, similarly to other conditions, [46] though our study was not designed to assess outcomes. Future studies will show the prognostic value of abnormal strain measurements and whether they normalize after cocaine cessation.…”

Section: Strain Analysismentioning

confidence: 98%

Detection of subclinical myocardial dysfunction in cocaine addicts with feature tracking cardiovascular magnetic resonance

Maceira

Guardiola²,

Ripoll

et al. 2020

Journal of Cardiovascular Magnetic Resonance

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Background Cocaine is an addictive, sympathomimetic drug with potentially lethal effects. We have previously shown with cardiovascular magnetic resonance (CMR) the presence of cardiovascular involvement in a significant percentage of consecutive asymptomatic cocaine addicts. CMR with feature-tracking analysis (CMR-FT) allows for the quantification of myocardial deformation which may detect preclinical involvement. Therefore, we aimed to assess the effects of cocaine on the left ventricular myocardium in a group of asymptomatic cocaine users with CMR-FT. Methods In a cohort of asymptomatic cocaine addicts (CA) who had been submitted to CMR at 3 T, we used CMR-FT to measure strain, strain rate and dyssynchrony index in CA with mildly decreased left ventricular ejection fraction (CA-LVEFd) and in CA with preserved ejection fraction (CA-LVEFp). We also measured these parameters in 30 age-matched healthy subjects. Results There were no differences according to age. Significant differences were seen in global longitudinal, radial and circumferential strain, in global longitudinal and radial strain rate and in radial and circumferential dyssynchrony index among the groups, with the lowest values in CA-LVEFd and intermediate values in CA-LVEFp. Longitudinal, radial and circumferential strain values were significantly lower in CA-LVEFp with respect to controls. Conclusions CA-LVEFp show decreased systolic strain and strain rate values, with intermediate values between healthy controls and CA-LVEFd. Signs suggestive of dyssynchrony were also detected. In CA, CMR-FT based strain analysis can detect early subclinical myocardial involvement.

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“…Myocardial deformation (strain) parameters, such as global longitudinal strain (GLS) and global circumferential strain (GCS), have emerged as sensitive markers of early subclinical myocardial dysfunction. They are strong, independent predictors of mortality in patients with heart disease, even after accounting for left ventricular ejection fraction (LVEF) and LGE burden [ 29 ]. Feature tracking (CMR-FT), which tracks myocardial borders over time on cine images, is well validated and evaluated in a wide range of cardiovascular disease [ 30 , 31 ], including the differentiation of LVH [ 32 ].…”

Section: Cmr Tissue Characterisation Techniquesmentioning

confidence: 99%

Cardiovascular Magnetic Resonance for the Differentiation of Left Ventricular Hypertrophy

Burrage

Ferreira

2020

Curr Heart Fail Rep

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Purpose of Review Left ventricular hypertrophy (LVH) is a common presentation encountered in clinical practice with a diverse range of potential aetiologies. Differentiation of pathological from physiological hypertrophy can be challenging but is crucial for further management and prognostication. Cardiovascular magnetic resonance (CMR) with advanced myocardial tissue characterisation is a powerful tool that may help to differentiate these aetiologies in the assessment of LVH. Recent Findings The use of CMR for detailed morphological assessment of LVH is well described. More recently, advanced CMR techniques (late gadolinium enhancement, parametric mapping, diffusion tensor imaging, and myocardial strain) have been used. These techniques are highly promising in helping to differentiate key aetiologies of LVH and provide valuable prognostic information. Summary Recent advancements in CMR tissue characterisation, such as parametric mapping, in combination with detailed morphological assessment and late gadolinium enhancement, provide a powerful resource that may help assess and differentiate important causes of LVH.

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Association of Feature-Tracking Cardiac Magnetic Resonance Imaging Left Ventricular Global Longitudinal Strain With All-Cause Mortality in Patients With Reduced Left Ventricular Ejection Fraction

Cited by 50 publications

References 5 publications

Cardiovascular Magnetic Resonance in the Oncology Patient

Cardiovascular Magnetic Resonance in the Oncology Patient

Detection of subclinical myocardial dysfunction in cocaine addicts with feature tracking cardiovascular magnetic resonance

Cardiovascular Magnetic Resonance for the Differentiation of Left Ventricular Hypertrophy

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