Association of Endometrial Thickness with Histopathological Pattern of Endometrium with Postmenopausal Bleeding

Krishnamoorthy, Parvathavarthini; Balakrishnan, Nandhini; Prasad, Geetha

doi:10.5005/jp-journals-10032-1151

Cited by 1 publication

(5 citation statements)

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“…Patients presented with age ranging from 44 to 72 years with maximum of 31.25% in age group of 46-50 years. This is similar to study by Parvathavarthini Krishnamoorthy et al, 7 Kothapally et al 10 Of these patients 57.5% were multiparous (parity >2), this is in accordance with study by Kothapally et al, Parvathavarthini Krishnamoorthy et al, Jyothsna Sravanthi et al 3 Regarding presentation of symptoms after menopause, maximum patients (53.75%) presented with PMB within 1 -5 years of menopause and 15% in 6-10 years.…”

Section: Discussionsupporting

confidence: 89%

“…23.75% had Endometrial hyperplasia which is in accordance with study by Pushpa Singh et al which showed 23.3%. 11 Adenocarcinoma was seen in 11.25% similar to findings in study by Pushpa et al which showed 13% 11 and 10% in study by Parvathavarthini et al and Kothapally et al 7,10 In our study 9 patients had Endometrial carcinoma, their age group ranged from 49 to 67 years. 1 patient was nulliparous and other 8 patients were multiparous (parity>2).…”

Section: Discussionsupporting

confidence: 88%

“…ET ranged from 6mm to 33mm with mean of 15 mm which was similar to study by Parvathavarthini Krishnamoorthy et al 7…”

Section: Discussionsupporting

confidence: 88%

“…In this study 28.75% had HT and DM compared to 20% HT and 11% DM in study by Jyothsna Sravanthi et al, 3 36% HT and 13% DM in study by Radha Nair et al 2 Transvaginal sonography showed ET>4mm in majority of cases (86.25%) similar to findings in study by Kothapally et al, 10 Radha Nair et al, 2 Parvathavarthini Krishnamoorthy et al 7 According to ACOG committee opinion no: 734, ET <4mm has a 99% negative predictive value for EM Ca. 9 Sonographic measurement of ET has to be done first in PMB to decide whether further investigations are needed to rule out malignancy.…”

Section: Discussionsupporting

confidence: 83%

“…5 Early diagnosis of EM Ca increases the 5-year survival rate up to 95%. 7 Evaluation of endometrium includes various modalities such as TVS, Hysteroscopy and guided biopsy, Dilatation and curettage, CT, MRI. But histopathology is the gold standard for definitive diagnosis.…”

Section: Etiology Of Postmenopausal Bleedingmentioning

confidence: 99%

See 4 more Smart Citations

Clinicopathological evaluation of patients with postmenopausal bleeding in a tertiary care center

Hemalatha¹,

Thenmozhi²,

S.³

2023

IJOGR

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Postmenopausal bleeding (PMB) is frequent finding in 5-10% of women in gynaecology clinic. About 10% of these patients have primary or secondary malignancy. PMB requires complete assessment to ensure the absence of malignancy and to identify and treat high risk patients such as those with endometrial hyperplasia.The aim of this study is to investigate the clinical significance and endometrial pathology in patients with PMB.A retrospective study on postmenopausal women visiting a tertiary care center between 2016 January to 2017 December was taken up for study. About 80 patients with PMB were selected and these patients were evaluated by pelvic USG, Endometrial biopsy and Endometrial histopathology.Maximum patients with PMB belonged to age group of 46-50 years (31.25%). 57.5% were multiparous (parity>2). About 53.75% had PMB 1 to 5 years after menopause. Endometrial thickness (ET) was > 4mm in 86.25%. Majority had ET between 5-10mm (58.75%). Histopathological analysis of endometrial curettings showed Proliferative phase in 35%, disordered proliferative phase in 17.5%, Atrophic Endometrium in 13.75% and endometrial carcinoma in 11.25%.Postmenopausal bleeding is an important symptom which requires evaluation to eliminate possibility of malignancy. Transvaginal sonography (TVS) is the first mode of investigation for PMB but Histopathology of Endometrium serves as gold standard for definitive diagnosis.

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Section: Discussionsupporting

confidence: 89%