Association of Depression and Anxiety with Oocyte and Sperm Numbers and Pregnancy Outcomes during in vitro Fertilization Treatment

Abstract

To estimate association of depression and anxiety scores with oocyte and sperm numbers and pregnancy rates during in vitro fertilization (IVF) treatment, 80 Turkish couples were administered the Spielberger State and Trait Anxiety and Beck Depression Inventories. A significant correlation (r = -.25) obtained between Depression and women's oocyte pickup data and number of oocytes, showed that low oocyte numbers w ere associated with higher Depression. No significant relation was found for sperm counts with Anxiety and Depression scores on the day of oocyte pickup and sperm collection, but sperm motility was weakly and inversely correlated with Depression scores. Women with high State Anxiety score on the oocyte pickup day had significant lower pregnancy rates, as did those with higher Depression. Counseling of couples by health professionals on fertility-related issues to be implemented in IVF units is advisable.

Pituitary-adrenal and sympathetic nervous system responses to psychiatric disorders in women undergoing in vitro fertilization treatment

“…However, it also has been confirmed that IVF is a highly stressful experience (5). Stress and distress have been found to be associated with a poorer ovarian functional response to IVF-treatment and with reduced fertilization, implantation, and live-birth rates (8,21). Differences in population and choice of questionnaires may explain the conflicting results.…”

Depression and state anxiety scores during assisted reproductive treatment are associated with outcome: a meta-analysis

“…The screening process is summarized in the study PRISMA flow chart (Figure 1). A total of 11 studies Gourounti et al, 2011;Gürhan et al, 2009;Hashemi et al, 2012;Karlidere et al, 2008;Li et al, 2011;Lintsen et al, 2009;Saravelos et al, 2016;Taguchi et al, 2015;Turner et al, 2013;Zaig et al, 2012) were included in the meta-analysis.…”

Impact of a group mind/body intervention on pregnancy rates in IVF patients

“…Women undergoing infertility treatments exhibit high anxiety and/or high depressive scores at the start of treatment as well as over the course of treatment (1)(2)(3)(4). Stress may also have a negative impact on pregnancy rates in women undergoing in vitro fertilization (IVF) (5)(6)(7)(8). A recent large study (9) did not reveal a relationship between distress and IVF outcome, so it is possible that there might be differences among patient populations or cultural influences on emotional expression.…”