Association of decreases in asthma mortality with increases in sales of inhaled corticosteroids

Sly, R. Michael

doi:10.1067/mai.2000.110470

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…The reduction in asthma mortality and morbidity with the regular use of maintenance medication has been well documented (19)(20)(21)(22)(23). In our study, we observed that only 22% of the uncontrolled patients used inhaled corticoids daily while 82% of the controlled patients did so.…”

Section: Discussionsupporting

confidence: 46%

Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

Santos

Oliveira

Faresin

et al. 2007

Braz J Med Biol Res

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Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled).

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Section: Discussionsupporting

confidence: 46%

Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

Santos

Oliveira

Faresin

et al. 2007

Braz J Med Biol Res

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“…Although a correlation between the reduction in asthma mortality and the widespread use of inhaled corticosteroids to control airway inflammation has been proposed by some authors, 25 - 27 no specific studies have been conducted in order to investigate that correlation. In Brazil, the Unified Health Care System has been providing inhaled corticosteroids for patients with persistent asthma since 2004, when the Primary Health Care Guidelines for Asthma and Rhinitis were published, with the objective of broadening the scope of the health care provided to such patients.…”

Section: Discussionmentioning

confidence: 99%

Trends in asthma mortality in the 0- to 4-year and 5- to 34-year age groups in Brazil

2017

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Objective: To provide an update on trends in asthma mortality in Brazil for two age groups: 0-4 years and 5-34 years.Methods: Data on mortality from asthma, as defined in the International Classification of Diseases, were obtained for the 1980-2014 period from the Mortality Database maintained by the Information Technology Department of the Brazilian Unified Health Care System. To analyze time trends in standardized asthma mortality rates, we conducted an ecological time-series study, using regression models for the 0- to 4-year and 5- to 34-year age groups.Results:There was a linear trend toward a decrease in asthma mortality in both age groups, whereas there was a third-order polynomial fit in the general population.Conclusions: Although asthma mortality showed a consistent, linear decrease in individuals ≤ 34 years of age, the rate of decline was greater in the 0- to 4-year age group. The 5- to 34-year group also showed a linear decline in mortality, and the rate of that decline increased after the year 2004, when treatment with inhaled corticosteroids became more widely available. The linear decrease in asthma mortality found in both age groups contrasts with the nonlinear trend observed in the general population of Brazil. The introduction of inhaled corticosteroid use through public policies to control asthma coincided with a significant decrease in asthma mortality rates in both subsets of individuals over 5 years of age. The causes of this decline in asthma-related mortality in younger age groups continue to constitute a matter of debate.

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The burden of asthma with specific reference to the United States

Beasley¹

2002

Journal of Allergy and Clinical Immunology

151

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Association of decreases in asthma mortality with increases in sales of inhaled corticosteroids

Cited by 3 publications

References 2 publications

Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

Trends in asthma mortality in the 0- to 4-year and 5- to 34-year age groups in Brazil

The burden of asthma with specific reference to the United States

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