Association of Controlling Nutritional Status Score With 2-Year Clinical Outcomes in Patients With ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Deng, Xingming; Zhang, Shuning; Shen, Shutong; Deng, Liyu; Shen, Li; Qian, Juying; Ge, Junbo

doi:10.1016/j.hlc.2020.02.017

Cited by 9 publications

(14 citation statements)

References 20 publications

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“…Leave-out one study sensitivity analysis showed that the pooling RR of MACEs ranged from 1.51 to 1.94 (all P values <.05). After removal of the Deng et al study 19 from the analysis, there was no significant heterogeneity (I 2 = 0.0%; P = .907). The values of high CONUT score in predicting MACEs were consistently observed in each named subgroup (Supplemental Table S2).…”

Section: Resultsmentioning

confidence: 93%

“…In the leave-out one study sensitivity analysis, the pooling RR of all-cause mortality ranged from 1.44 to 1.52 (all P values <.05). The significant heterogeneity was substantially reduced after excluding the Deng et al study 19 from the analysis. Moreover, each category of CONUT score increase (from mild to severe malnutrition) conferred a 28% greater risk of MACEs in patients with ACS.…”

Section: Resultsmentioning

confidence: 99%

“…Twenty-four articles were further excluded after application of the inclusion and exclusion criteria. Finally, 12 studies 8-13,19-24 were included in the present meta-analysis (Figure 1).

Figure 1.Flow chart showing studies selection process.…”

Section: Resultsmentioning

confidence: 99%

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Association of Controlling Nutritional Status Score With Adverse Outcomes in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis

Huang

Sun

et al. 2022

Angiology

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This systematic review and meta-analysis sought to examine the association between the controlling nutritional status (CONUT) score and adverse outcomes in patients with coronary artery disease (CAD). PubMed and Embase databases were searched for eligible studies from their inceptions to December 12, 2021 to identify studies investigating the association of the CONUT score with major adverse cardiovascular events (MACEs) and all-cause mortality in CAD patients. Twelve studies (36,198 CAD) patients satisfied the criteria. Comparison of the high with low CONUT score, the pooled multivariate adjusted risk ratios (RR) was 1.78 (95% confidence intervals [CI] 1.36-2.32) for MACEs and 1.45 (95% CI 1.27–1.66) for all-cause mortality, respectively. When compared with patients with normal nutrition, malnourished (defined by the CONUT score ≥2) patients conferred a 52% increased risk of MACEs. Additionally, per point CONUT score increment was associated with 15% and 11% higher risk of MACEs and all-cause mortality, respectively. Higher CONUT score independently predicts the MACEs all-cause mortality in CAD patients. Estimation of nutritional status using the CONUT score could be helpful for improving risk classification of CAD.

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Section: Resultsmentioning

confidence: 93%

Section: Resultsmentioning

confidence: 99%

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Association of Controlling Nutritional Status Score With Adverse Outcomes in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis

Huang

Sun

et al. 2022

Angiology

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“…Согласно другому исследованию по оценке связи развития неблагоприятных событий с типом питания у пациентов после первичного ИМ (медиана наблюдения 24,6±12 мес.) было показано, что при отсутствии модификации исходных диетических стереотипов пациентов, сложившихся до развития ИМ, ОР повторного ИМ составляет 12,09 (ДИ: 5,09-28,7; р<0,001) [17].…”

Section: результатыunclassified

Healthy nutrition in secondary prevention after myocardial infarction. What to focus on?

Barbarash

Sedykh

Petrova

et al. 2022

Cardiovasc Ther Prev

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Rationalization of dietary behavior in patients after myocardial infarction is the subject of numerous discussions. Despite the proven preventive effect of a healthy diet and the benefits of certain foods in cardiovascular diseases, this type of intervention is still underused. The aim of this review was to analyze current approaches to modifying the nutrition of patients within the secondary prevention of myocardial infarction. For this, 903 publications from PubMed/MEDLINE database over the past 5 years were studied. The Mediterranean diet demonstrated the highest efficacy and safety in preventing athero-thrombotic events among existing dietary patterns. However, its wide reproducibility in different regions is associated with a number of limitations. Government programs to modify and support a healthy diet beyond the conventional low-cholesterol diet may be promising in secondary prevention, especially if patients are properly monitored and motivated.

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“…Latest data indicate that the prevalence of malnourished patients is also common in coronary artery disease (9). However, few studies have addressed the prognostic effect of malnutrition in patients with STEMI (10). Identifying patients at risk for poor prognosis in the future may help to implement therapeutic interventions, change modifiable risk factors, and increase survival rates.…”

Section: Introductionmentioning

confidence: 99%

Prognostic performance of Controlling Nutritional Status score in patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention

Zengin¹,

Karataş²,

Çanga³

et al. 2022

The Anatolian Journal of Cardiology

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Objective: The effect of malnutrition in patients with ST segment elevation myocardial infarction (STEMI) is not fully understood. In this study, we tried to investigate the prognostic consequence of the Controlling Nutritional Status (CONUT) score in patients with STEMI. Methods: In this study, we evaluated the CONUT scores of 1,028 patients with STEMI and examined its relationship with major adverse cardiovascular events (MACE) (all-cause mortality, myocardial reinfarction, and vessel revascularization) during a period of 19.9±10.3 months. Patients with CONUT score ≥5 were defined as severely malnourished. Predictors of MACE were assessed by Cox regression analysis, and p<0.05 was considered to indicate statistical significance. Results: MACE was observed in a total of 147 (14.3%) patients. MACE was more frequent in the group with a higher CONUT score (33.3% vs. 10.9%, p<0.001). CONUT score ≥5 was an independent predictor of MACE in the Cox regression analysis (hazard ratio=2.50, 95% confidence interval: 1.61-3.90, p<0.001). Low ejection fraction, Killip class ≥3 at presentation, thrombolysis in myocardial infarction flow grade <3 after intervention, left main artery involvement, and low hemoglobin levels were other independent predictors of MACE in the long-term follow-up. Kaplan-Meier curves showed decreased MACE free survival rates in the high CONUT score group at a mean 19.9±10.3 months' follow-up duration (log-rank p<0.01). Conclusion: Malnutrition was strongly associated with poor outcomes in patients with STEMI treated using primary percutaneous coronary intervention.

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Association of Controlling Nutritional Status Score With 2-Year Clinical Outcomes in Patients With ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Cited by 9 publications

References 20 publications

Association of Controlling Nutritional Status Score With Adverse Outcomes in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis

Association of Controlling Nutritional Status Score With Adverse Outcomes in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis

Healthy nutrition in secondary prevention after myocardial infarction. What to focus on?

Prognostic performance of Controlling Nutritional Status score in patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention

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