Association of Atrial Fibrillation and Cancer

Rahman, Faisal; Ko, Darae; Benjamin, Emelia J.

doi:10.1001/jamacardio.2016.0582

Cited by 41 publications

(31 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is a close interplay between NVAF and cancer. 18 These 2 entities commonly co-exist in elderly patients, share certain risk factors, and may be clinically silent. As such, it is not surprising that evaluation of therapy-related GI bleeding may unveil a proportion of previously unrecognized malignancies.…”

Section: Cardio-gastro-oncology: a Complex Cross-roadsmentioning

confidence: 99%

Gastrointestinal Bleeding With Oral Anticoagulation: Understanding the Scope of the Problem

Vaduganathan

Bhatt

2017

Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

Section: Cardio-gastro-oncology: a Complex Cross-roadsmentioning

confidence: 99%

Gastrointestinal Bleeding With Oral Anticoagulation: Understanding the Scope of the Problem

Vaduganathan

Bhatt

2017

Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

“…Notably, new-onset AF may in turn increase the risk of subsequent cancer, particularly within the first 3 months following diagnosis of AF [3,4]. This effect is not well-understood but may be related to shared risk factors, increased detection of malignancies due to increased health care exposure, or to the unmasking of occult GI malignancies by anticoagulation [5].…”

Section: Introductionmentioning

confidence: 99%

Management of atrial fibrillation in patients taking targeted cancer therapies

et al. 2017

View full text Add to dashboard Cite

Atrial fibrillation (AF) is frequently observed in patients being treated for cancer and can lead to increased morbidity and mortality in this population. With the use of newer, targeted cancer therapies, several drug-drug interactions have emerged that complicate the use of antiarrhythmic drugs (AADs) in patients with active malignancy. Moreover, specific targeted therapies such as ibrutinib may contribute directly to the development of AF. The decision to pursue systemic anticoagulation can be challenging in patients with malignancy due to a number of factors, including the need for frequent procedures, the presence of malignancy-related risk factors for bleeding, and limited data regarding the safety of the novel oral anticoagulants (NOACs) in cancer patients. This review describes the challenges associated with AF management in patients with cancer and highlights a number of important drug-drug interactions that can impact patient management.

show abstract

“…The most common causes of AF are hypertensive heart disease, coronary heart disease, diabetes, hyperthyroidism, smoking, and alcohol abuse [ 4 - 5 ]. Recent studies have shown that it can be used as a marker for occult cancer [ 4 , 6 ] and may also help in diagnosing patients with asymptomatic or oligosymptomatic brain tumors. Here, we present an interesting case of a patient with no risk factors for AF, and the cause of his new AF was likely his brain tumor.…”

Section: Introductionmentioning

confidence: 99%

Brain Tumor Causing Atrial Fibrillation in an Otherwise Healthy Patient

Pawar

Vasanwala

Chua

2017

Cureus

View full text Add to dashboard Cite

We report a case of a 57-year-old man who presented with an episode of syncope resulting in an accident. On presentation, he was found to have atrial fibrillation (AF). A brain imaging done to exclude intracranial hemorrhage revealed a brain tumor instead. Recently, AF has been used as a marker for occult cancer. Thus, we hypothesize that AF in our patient was a result of the existing brain tumor and not simply a coincidence. AF may help in diagnosing brain tumors in asymptomatic or oligosymptomatic patients at an early stage, decreasing mortality and morbidity significantly.

show abstract

Association of Atrial Fibrillation and Cancer

Cited by 41 publications

References 23 publications

Gastrointestinal Bleeding With Oral Anticoagulation: Understanding the Scope of the Problem

Gastrointestinal Bleeding With Oral Anticoagulation: Understanding the Scope of the Problem

Management of atrial fibrillation in patients taking targeted cancer therapies

Brain Tumor Causing Atrial Fibrillation in an Otherwise Healthy Patient

Contact Info

Product

Resources

About