Association of Anthropometric Measurements, Hemoglobin Level and Salivary Parameters among Caries-free and S-ECC Children

Joshi, N.V.; Deshpande, Anshula; Wadhwa, Medha; Jain, Arpit; Patel, Kinjal S; Sudani, Urvashi

doi:10.5005/jp-journals-10005-2144

Cited by 3 publications

(2 citation statements)

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“…Notably, children suffering from severe dental caries exhibited low hemoglobin levels, a condition that, if persistent, could result in anemia. [41] Animal studies have provided valuable insights into the role of iron in dental caries. These experiments have shown that the administration of iron compounds like FeSO4 or FeCl3 can reduce the incidence of dental caries compared to that in control groups [42].…”

Section: S-eccmentioning

confidence: 99%

Iron Deficiency Anemia and Its Impact on Oral Health—A Literature Review

Velliyagounder,

Chavan,

Markowitz

2024

Dentistry Journal

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Oral disease interventions primarily focus on behavioral changes like dietary improvements and ensuring better oral hygiene. However, recognizing the influence of biological factors, including genetics and early-life nutrition, is crucial. Iron deficiency (ID) and its advanced form, iron deficiency anemia (IDA), affect nearly two billion people globally, especially children and pregnant women. We conducted a comprehensive search using Medline via EndNote and Web of Science, employing keywords related to iron deficiency anemia (IDA), and we identified 36 studies deemed relevant for inclusion in this literature review. IDA prevalence is notably high among pregnant women and young children. Both IDA and early-childhood caries (ECC) disproportionately affect impoverished populations, highlighting the socioeconomic dimension of this issue. IDA presents with various oral mucosal changes and is closely linked to candidiasis. Additionally, IDA can hinder tooth development and weaken the immune response. Multiple population surveys have revealed a significant association between ECC and IDA. While some studies have explored the IDA–periodontal disease link, the current evidence is relatively limited in its robustness. In conclusion, more comprehensive longitudinal studies are essential to deepen our understanding of the IDA–oral disease connection. Investigating the underlying biological mechanisms is critical to developing effective interventions, particularly for vulnerable populations affected by IDA.

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Section: S-eccmentioning

confidence: 99%

Iron Deficiency Anemia and Its Impact on Oral Health—A Literature Review

Velliyagounder,

Chavan,

Markowitz

2024

Dentistry Journal

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“…It has been shown that children with dental caries, aside from presenting with low saliva pH [9], also have anemia [10]. Furthermore, Deshpande et al observed concurrent low hemoglobin and saliva pH levels among children with severe dental caries in comparison to caries-free children [12]. Studies on the correlation between saliva pH and hemoglobin levels among pregnant women are scarce.…”

Section: Introductionmentioning

confidence: 99%

Biochemical Changes in Salivary pH and Its Correlation to Hemoglobin Levels, Calcium and Phosphate Ion Concentrations among Pregnant Women, Tanzania: A Cross-Sectional Study

Mbembela,

Ngarashi,

Nyamuryekung’e

2023

Oral

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Background: Surveys in Tanzania show that pregnant women have a significant burden of oral disease, although there is still little literature on the variation of their intraoral electrolytes. The present study investigated changes in salivary calcium (Ca2+), phosphate (PO43−), and hydrogen (H) ions during pregnancy and the correlation between salivary pH and hemoglobin levels. Methodology: A cross-sectional study involved sixty (60) pregnant women stratified by trimester and twenty (20) non-pregnant women attending an antenatal clinic at Mnazi Mmoja Hospital. Consecutive sampling was used, saliva was collected, and electrolyte levels were measured. Gestation age was the independent variable, whereas saliva pH and calcium and phosphate ion concentrations and hemoglobin levels were the dependent variables. Results: A difference in calcium concentration (z = −3.145, p = 0.001) and salivary pH (t = −2.49, p = 0.014) was observed between pregnant and non-pregnant women. Kruskal–Wallis tests for saliva Ca2+ and PO43− and ANOVA for saliva pH revealed differences in concentrations of saliva Ca2+, PO43−, and pH levels between trimester groups (saliva Ca2+ (H = 9.91, df = 3, p = 0.019), saliva PO43− (H = 12.36, df = 3, p = 0.006), saliva pH (F (3.76) = (16.42); p < 0.001)). Pearson’s correlation tests showed no association between salivary pH and hemoglobin levels. Conclusions: Pregnancy is associated with a reduction in saliva pH and saliva calcium levels with a progressive increase in the magnitude of reduction from the first trimester to the third trimester. Saliva phosphate reduction was noticed during the third trimester only and saliva pH levels were independent of hemoglobin levels.

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