Association between type 1 diabetes and periodontal health

Popławska-Kita, Anna; Siewko, Katarzyna; Szpak, Piotr; Król, Beata; Telejko, Beata; Klimiuk, Piotr Adrian; Stokowska, W; Górska, Maria; Szelachowska, Małgorzata

doi:10.1016/j.advms.2014.01.002

Cited by 45 publications

(52 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This results in compromised wound healing and increased periodontal tissue destruction in diabetes mellitus patients. This study is in accordance with study done by Poplawaska-Kita A et al, who reported that there was an increased risk of periodontitis in patients with diabetes mellitus [21]. Also, the reduction in salivary pH which was evident in our study may increase the growth of periodontal-pathogens which is in accordance with that of Takahashi et al, Fujikawa et al, and Galgut [22][23][24][25].…”

Section: Discussionsupporting

confidence: 93%

Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-sectional Study

Seethalakshmi

Reddy

Asifa

et al. 2016

JCDR

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 93%

Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-sectional Study

Seethalakshmi

Reddy

Asifa

et al. 2016

JCDR

View full text Add to dashboard Cite

“…Then, we excluded 76 articles due to original data expressed with figures, duplicated data, or no original data. Finally, 20 articles (23 case-control studies) met the criteria and were included in this meta-analysis [1, 7, 21–25, 35–47] (S1 Appendix), involving 1631 T1DM patients and 1429 healthy controls. The specific characteristics of the 23 studies are shown in Table 1.…”

Section: Resultsmentioning

confidence: 99%

“…Type 1 diabetes mellitus (T1DM) is a systemic disease leading to abnormal fat, carbohydrate, and protein metabolism due to insulin deficiency [1]. Metabolic proinflammatory disorder, such as chronic hyperglycemia and increased levels of circulating cytokines, suggests immunological disturbances [2–5], which seriously affects the quality of life of the patients and imposes a large economic burden on the national health care system [6].…”

Section: Introductionmentioning

confidence: 99%

The change of serum tumor necrosis factor alpha in patients with type 1 diabetes mellitus: A systematic review and meta-analysis

et al. 2017

View full text Add to dashboard Cite

ObjectiveThe aim of this study was used meta-analysis to investigate changes of serum tumor necrosis factor-alpha (TNF-α) in patients with type 1 diabetes mellitus (T1DM).MethodsRelevant literatures were identified from PubMed, Cochrane Library, CNKI, WanFang and Chinese-Cqvip databases (published from January 1, 1999 to September 30, 2016). Eligible reports were included for pooled analysis of serum TNF-α level and subgroup analysis was performed in relation with age, disease duration and ethnicity.ResultsA total of 23 articles (1631 T1DM cases, 1429 healthy controls) were included for this meta-analysis. Compared with the controls, the patients had significantly increased serum TNF-α level (P < 0.001). Similar results were also found among all subgroup analysis of different age, disease duration and ethnicity (with the exception of Asian) (all P < 0.05). Regression analysis indicated that age (P = 0.680), disease duration (P = 0.957), and ethnicity (P = 0.526) of patients were not significant impact factors for the high heterogeneity. The results were stable according to the sensitivity analysis and no publication bias existed in this meta-analysis.ConclusionsSerum TNF-α level in T1DM patients has significantly elevated among all age, disease duration and ethnicity groups.

show abstract

“…Diabetic individuals, both type l and type 2, experience a higher incidence of periodontitis and the severity of the disease correlates with the duration of diabetes and glycemic control reflected by glycated hemoglobin (HbAlc) levels in the blood [5]. Type l diabetes has been recognized as an important modifier of periodontal disease [6, 7]. Numerous factors related to diabetes have been proposed to increase the severity of periodontal disease in diabetic individuals, such as vascular abnormalities, neutrophil dysfunction, nonenzymatic glycosylation, altered collagen metabolism, and altered monocytic response [8].…”

Section: Introductionmentioning

confidence: 99%

Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes

Buzinin

Alabsi

Tan

et al. 2014

The Scientific World Journal

View full text Add to dashboard Cite

The association between diabetes mellitus and chronic periodontal disease has long been established. Most of the researches linking these two very common chronic diseases were based on type 2 diabetes mellitus and chronic periodontal disease. However, this study was conducted to investigate the association between type 1 diabetes and chronic periodontal disease in Malaysian subjects. Forty-one Malaysian subjects, of which 20 subjects were type 1 diabetics and with chronic periodontal disease (test group) and 21 subjects with only chronic periodontal disease (control group), were included in the study. Periodontal parameters and plaque samples for microbiological evaluation were done at baseline, 2 and 3 months after nonsurgical periodontal therapy. Blood samples were taken from only the test group and evaluated for HbA1c at baseline and 3 months after periodontal therapy. There were no statistically significant difference in periodontal parameters between groups (P>0.05) and no significant improvement in the level of HbA1c in the test group. Microbiological studies indicated that there were significant reductions in the levels of the tested pathogens in both groups. The results of our study were similar to the findings of several other studies that had been done previously.

show abstract

Association between type 1 diabetes and periodontal health

Cited by 45 publications

References 33 publications

Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-sectional Study

Correlation of Salivary pH, Incidence of Dental Caries and Periodontal Status in Diabetes Mellitus Patients: A Cross-sectional Study

The change of serum tumor necrosis factor alpha in patients with type 1 diabetes mellitus: A systematic review and meta-analysis

Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes

Contact Info

Product

Resources

About