Abstract:Bakground: The level of antituberculosis (TB) agents and risk of anti-TB drug-induced liver injury could be predicted by patients' genotype polymorphism of the xenobiotic-metabolizsing enzymes. For example, detection of N-acetyltransferase 2 genotype in TB-patients is very valuable in this relation. Aim: To find the meaning of cyptochrome P-4503A4*1B (CYP3A4*1B) polymorphism in TB-patients. Materials and methods: CYP3A4*1B genotype was detected with the help of polymerase chain reaction among 105 patients with… Show more
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