Association between thyroid hormones and body fat in euthyroid subjects

Abstract

Grouped according to BMI, overweight and obese subjects have similar thyroid hormones compared to those with normal weight. Body composition parameters increase with the elevation of FT3, and FT3 is associated with body fat parameters in euthyroid subjects.

Association between thyroid hormone levels, body composition and insulin resistance in euthyroid subjects with normal thyroid ultrasound: The Kangbuk Samsung Health Study

“…Thyroid hormones play crucial roles in the control of energy homoeostasis and thermogenesis and can therefore influence body composition . Hypothyroidism is associated with weight gain, whereas hyperthyroidism is associated with increased metabolic rate and weight loss .…”

“…In contrast, the changes in body composition might influence thyroid hormone levels. Previous studies have evaluated the associations between thyroid hormone levels and anthropometric markers . Serum thyrotropin (thyroid‐stimulating hormone, TSH), triiodothyronine (T3) and free T3 (FT3) levels were positively associated with body mass index (BMI) and waist circumference (WC) in euthyroid subjects .…”

“…Many previous studies have evaluated the associations between thyroid hormone levels and BMI, WC or waist‐to‐hip ratio, because these are widely used metrics for obesity. However, few studies have used body composition such as body fat mass and body fat percentage (BFP) as surrogate parameters . In addition, skeletal muscle is a major target of thyroid hormones .…”

Indices of Central and Peripheral Obesity; Anthropometric Measurements and Laboratory Parameters of Metabolic Syndrome and Thyroid Function

“…The association of obesity and IR is an extensive clinical condition, and insulin resistance (IR) also integrates these pathologies. Moreover, recent new studies have shown a relation between thyroid function tests and MetS parameters (9,10). The aim of our study was to explore the relationship or differences between anthropometric indices that assess central obesity and peripheral obesity, and the relationship among IR, MetS and thyroid function in female obese and healthy control subjects.…”

Evaluation of changes in vitamin B12, ferritin, folic acid, and thyroid hormone levels after sleeve gastrectomy

“…A positive correlation between adiposity parameters and TSH and fT3 has been shown in several studies. Ren et al suggested that dysfunction of adipose tissue is the main factor responsible for changes in the homeostasis of thyroid hormones, which is borne out by the observation that weight loss reverses or mitigates these changes (8).…”