Association between surgical repair of aortic aneurysms and the diagnosis of subsequent cardiovascular diseases

Wang, Jen-Chun; Chien, Wu Chien; Chung, Chi Hsiang; Lin, Cheng‐I; Hsu, Chin Wang; Lin, Chin; Tsai, Shih‐Hung

doi:10.1016/j.jjcc.2019.12.005

Cited by 2 publications

(1 citation statement)

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“…Reactive oxygen species are generated by endothelial cells during migraine attacks [ 11 , 12 , 13 ]. Consistent with previous studies, we also identified CAD and malignancy as risk factors for AAA development [ 42 , 43 , 44 ]. A previous study demonstrated an association between spontaneous coronary artery dissection (SCAD) and migraine.…”

Section: Discussionsupporting

confidence: 91%

The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study

Lin

Tung

Wang

et al. 2021

IJERPH

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Previous studies have indicated that patients with migraine have a higher prevalence of risk factors known to be associated with cardiovascular diseases. There are also shared epidemiology and molecular mechanisms between migraine and abdominal aortic aneurysm (AAA). We hypothesized that patients with migraine could have an increased risk of AAA. To test this hypothesis, we used the National Health Insurance Research Database (NHIRD) to evaluate whether associations exist between migraine and AAA. The data for this nationwide population-based retrospective cohort study were obtained from the NHIRD in Taiwan. The assessed study outcome was the cumulative incidence of AAA in patients with migraine during a 15-year follow-up period. Among the 1,936,512 patients from the NHIRD, 53,668 (2.77%) patients were identified as having been diagnosed with migraine. The patients with migraine had a significantly higher cumulative risk of 3.558 of developing an AAA 5 years after the index date compared with the patients without migraine. At the end of the 15-year follow-up period, a significantly higher incidence of AAA (0.98%) was observed in the patients with migraine than in those without migraine (0.24%). We revealed an association between the development of migraine and AAA.

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