Association between retinal vascular measures and brain white matter lesions in schizophrenia

Korann, Vittal; Suhas, Satish; Appaji, Abhishek; Nagendra, Bhargavi; Padmanabha, Ananth; Jacob, Arpitha; Devi, Priyanka; Bharath, Rose Dawn; Kumar, Vijay; Varambally, Shivarama; Venkatasubramanian, Ganesan; Rao, Shyam Vasudeva; Webers, Caroll; Berendschot, Tos T. J. M.; Rao, Naren P.

doi:10.1016/j.ajp.2022.103042

Cited by 6 publications

(1 citation statement)

References 64 publications

(78 reference statements)

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“…And WML is also seen in schizophrenia [43][44][45][46][47] and alcohol related psychiatric disorder [48][49][50][51][52][53] .…”

Section: Inference Of Mechanismsmentioning

confidence: 99%

Plasma Phosphoethanolamine Levels as a Biomarker for Monitoring Major Depressive Disorder

Kawamura,

Nakata,

Harada

et al. 2023

Preprint

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This study is the first to identify a promising candidate monitoring biomarker for major depressive disorder (MDD), plasma phosphoethanolamine (PEA) concentrations. A naturalistic observational study in clinical psychiatry was conducted with Japanese subjects between 2011 and 2020. Out of the 576 patients, 295 had depressive disorders, 264 had psychiatric disorders other than depression, and 17 had physical disorders without psychiatric disorders. In 170 patients with MDD only, in whom remission was easily identified, plasma PEA levels were measured at two or more time points. These levels dropped significantly in depressive episodes, increased as remission approached and were significantly higher in remission. Psychiatric diagnosis alone explained 38% of the variance in plasma PEA concentrations. Receiver operating characteristic (ROC) curve analysis also showed sufficient discriminatory power to detect depression, with an area under the curve (AUC) of 0.84 (95% confidence interval (CI): 0.80-0.87). Further researches are needed.

show abstract

“…And WML is also seen in schizophrenia [43][44][45][46][47] and alcohol related psychiatric disorder [48][49][50][51][52][53] .…”

Section: Inference Of Mechanismsmentioning

confidence: 99%

Plasma Phosphoethanolamine Levels as a Biomarker for Monitoring Major Depressive Disorder

Kawamura,

Nakata,

Harada

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

Retinal microvasculature in schizophrenia: A meta-analysis with trial sequential analysis of studies assessing vessel density using Optical Coherence Tomography Angiography

Janti

Tikka

2023

Asian Journal of Psychiatry

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Linked patterns of interhemispheric functional connectivity and microstructural characteristics of the corpus callosum in antipsychotic-naive first-episode schizophrenia

Tao

Xiao

et al. 2023

Asian Journal of Psychiatry

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Association between retinal vascular measures and brain white matter lesions in schizophrenia

Cited by 6 publications

References 64 publications

Plasma Phosphoethanolamine Levels as a Biomarker for Monitoring Major Depressive Disorder

Plasma Phosphoethanolamine Levels as a Biomarker for Monitoring Major Depressive Disorder

Retinal microvasculature in schizophrenia: A meta-analysis with trial sequential analysis of studies assessing vessel density using Optical Coherence Tomography Angiography

Linked patterns of interhemispheric functional connectivity and microstructural characteristics of the corpus callosum in antipsychotic-naive first-episode schizophrenia

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