Association between obesity and the severity of ambulatory hypertension in children and adolescents

Babinská, Katarína; Kovács, László; Jankó, Viktor; Dallos, Tomáš; Feber, Janusz

doi:10.1016/j.jash.2012.08.002

Cited by 46 publications

(24 citation statements)

References 26 publications

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“…We observed that every 1 kg increase in current body weight leads to an estimated SBP and DBP increase of 0.618 and 0.364 mm Hg, respectively, after excluding the height indicator, whereas a decrease of 0.173 mm Hg in SBP and 0.164 mm Hg in DBP was found per 1-cm increase in waist circumference. Although previous findings found that weight and BMI have a positive association with BP levels [23,61,62,63], the present weak inverse association between waist circumference and SBP/DBP was not in accordance with other reports [23,62]. It has also been reported that the height indicator is positively correlated with BP [23,59], though we were unable to find any correlation.…”

Section: Discussioncontrasting

confidence: 99%

Does Low Birth Weight Predict Hypertension and Obesity in Schoolchildren?

Zarrati¹,

Shidfar²,

Razmpoosh³

et al. 2013

Ann Nutr Metab

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Background: Birth weight appears to play a role in determining high blood pressure (BP) and obesity during childhood. The purpose of this study is to investigate the association between birth weight and later obesity and hypertension among 10- to 13-year-old schoolchildren. Methods: A total of 1,184 primary school students were selected from 20 randomized schools between 2011 and 2012 in Iran. Height, weight, waist circumference and BP were measured using standard instruments. Data were analyzed using stepwise regression and logistic regression models. Results: 13.5% of children had a history of low birth weight. First-degree family history of obesity, excessive gestational weight gain and birth weight were significantly correlated with overweight/obesity and abdominal obesity (p = 0.001), whereas only birth weight was associated with high BP (p = 0.001). An inverse correlation was found between waist circumference and systolic/diastolic BP. The duration of breastfeeding in children with low birth weight was inversely correlated with obesity/overweight, abdominal obesity and hypertension. Conclusion: The results suggests that birth weight is inversely associated with BP and more so with obesity and abdominal obesity. The duration of having been breastfed could have an influence on later hypertension, obesity and abdominal obesity. Further results are needed to test these correlations as well as diagnosing early life factors to prevent young adult overweight/obesity or hypertension.

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Section: Discussioncontrasting

confidence: 99%

Does Low Birth Weight Predict Hypertension and Obesity in Schoolchildren?

Zarrati¹,

Shidfar²,

Razmpoosh³

et al. 2013

Ann Nutr Metab

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“…28 The possible mechanisms for the occurrence of high blood pressure in high serum uric acid includes: (a) uric acid induced activation of rennin angiotensin system and action on glomerular apparatus (b) increased insulin resistance and increased insulin level, causing decreased excretion of uric acid, sodium, potassium from kidney tubules and (c) uric acid action in proliferation of vascular smooth muscles, endothelial dysfunction with decrease nitric acid production. [29][30][31][32][33][34][35] Initially uric acid causes constriction of vessels by activation of the renninangiotensin system and decreased circulating nitric oxide by endothelial dysfunction which results in hypertension. This hypertension type is salt resistant and this can be reversed by decreasing uric acid.…”

Section: Discussionmentioning

confidence: 99%

Hyperuricaemia and essential hypertension: a case control study in Southern Rajasthan

et al. 2016

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INTRODUCTIONLife is not merely to be alive, but to be healthy and wealthy. Despite incredible improvement in health since 1950, cardiovascular disease remains among the leading causes of death worldwide. Hypertension (HT) is the most common risk factor for cardiovascular morbidity and mortality. This positive relationship between blood pressure (BP) and cardiovascular risk has been shown to exist not only in those with higher BP but also in individuals with high-normal BP/prehypertension. 1 Prehypertension as the name suggests that it precedes the hypertension. Trends in hypertension prevalence in India have shown a high prevalence of hypertension in both urban and rural areas. The prevalence rates of hypertension among urban population are 36.4% and rural people are 21.2%. 2 ABSTRACTBackground: Hypertension is one of the current emerging community health problems, which is very common affecting one in four individuals. Hyperuricemia is predictive for the development of both hypertension and coronary artery disease. Since there are various etiological factors associated with hypertension so it is very difficult to predict which one is the most common cause of hypertension. Little or no information is present in the population of Rajasthan, on the association between serum uric acid and essential hypertension. Hence this study is carried out to investigate the existence of an association between serum uric acid and essential hypertension. Methods: In this hospital based case control study, a total of 75 newly diagnosed essential hypertensive cases, 75 prehypertensive cases and 50 normotensive healthy controls, aged 20-50 years of both sexes were enrolled after excluding gout, diabetes mellitus, cardiovascular diseases, renal diseases, metabolic syndrome, secondary hypertension or history of having relevant drugs by taking detailed history and physical examination. Serum uric acid was measured in all study cases as well as control subjects. Results:The results of our study revealed that the mean serum uric acid level and the frequency of subjects with increased serum uric acid level were significantly higher in newly diagnosed cases of essential hypertension as compared to prehypertensive and normotensive controls (p< 0.001). Serum uric acid correlated positively with systolic blood pressure (SBP) (r= + 0.23, p<0.05) and diastolic blood pressure (DBP) (r= + 0.09, p>0.05). These results indicate a definite association between hyperuricaemia and essential hypertension. Conclusions: In the present study, Elevated level of SUA is significantly linked with PreHT and EHT after controlling various confounding factors. The present study showed that the number of hyperuricaemic individuals and mean SUA level were significantly higher in newly diagnosed cases of hypertension as compared to prehypertensive and normotensive control.

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“…O besity is associated with elevated blood pressure (BP) in children and adolescents [1,2], and weight reduction has been accompanied with a reduction in clinic BP [3][4][5]. Ambulatory BP (ABP) is the most precise measure to evaluate the BP burden [6][7][8], and weight-associated reduction in ABP has been related to a reduction in risk factors of cardiovascular disease in adults [9].…”

Section: Introductionmentioning

confidence: 99%