Association between monosodium glutamate intake and sleep-disordered breathing among Chinese adults with normal body weight

Abstract

Association between monosodium glutamate intake and sleep-disordered breathing among Chinese adults with normal body weight Nutrition, 2013; 29(3):508-513 © 2013 Elsevier Inc. All rights reserved. NOTICE: this is the author's version of a work that was accepted for publication in Nutrition. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Nutrition, 2013; 29 (3)

Knowledge and Awareness of Monosodium Glutamate (Ajinomoto Salt) among Students

“…One limitation of the study was that the respondents may not have been representative of all the students in the entire region [27]. However, although the respondents may not reflect them all, they may be representative of those from Chennai.…”

Worldwide flavor enhancer monosodium glutamate combined with high lipid diet provokes metabolic alterations and systemic anomalies: An overview

“…Higher incidence of syndrome X has been positively linked with 1 g higher consumption of MSG in the diet [ 13 ]. Besides the above pieces of evidence, MSG also exerts diverse destructive impact ( Table 1 ) on human health, such as Type 2 diabetes, by activating N-methyl- d -aspartate receptor (NMDAR) to disturb the functions of β-cell in the pancreas [ 128 , 129 ], hyperphagia, hyperleptinemia, and dyslipidemia by altered lipid profiles with increased leptin level [ 130 , 35 , 131 ], sleep-disordered breathing (SDB), increased chances of gastroesophageal reflux disease and mandibular retrognathia [ 43 , 132 , 133 ], etc. Moreover, MSG also de-activates normal thermogenesis processes in brown adipose tissue and thereby leads to altered regulation of thermogenesis [ 134 ].…”

“…[ 137 , 136 ] iv. [ 129 ] Hyperphagia, hyperleptinemia and dyslipidemia Altered metabolic activities, obesity, IR, increased levels of leptin or incompetent binding of leptin to its receptors and altered lipid profile [ 35 , 130 , 131 ] Sleep-disordered breathing (SDB) Obstruction in respiratory system and increase movement of gastrointestinal tract also leads to SDB via higher incidence of GERD [ 43 , 132 , 133 ] De-activation of thermogenesis Reduction of thermogenesis in BAT and thereby decreases the normal thermoregulatory mechanism [ 134 ] Nociceptive response Increase interstitial concentration of glutamate in the facial muscle with musculoskeletal disorders followed by nociceptive response [ 35 ] Allergy, eczema and MSG symptom complex MSG acts as pseudo allergens to cause allergic responses [ 35 , 46 , 138 , 12 ] …”

“…It occurred due to the obstruction of the pharynx or breathing pause or insufficient ventilation during the sleeping period and produced snoring without disturbing the sleep and depended upon an individual’s age and body weight. Furthermore, escalated movement of the gastrointestinal tract by MSG leads to the higher incidence of gastroesophageal reflux disease (GERD), which also linked with OSA, are more common among Asians, according to their cranial architectural aspects and a higher rate of mandibular retrognathia [ 43 , 132 , 133 ].…”

Epidemiological Studies of Monosodium Glutamate and Health

“…Several risk factors are known for SDB and OSA, such as age and body weight [27]. Recently, the SDB was also associated with the consumption of MSG in the Jiangsu Nutrition (JIN) Cohort Study amount Chinese adults in normal weight [28,29]. Furthermore, MSG was associated with snoring in normal weight.…”